Results 101 to 110 of about 6,491,660 (243)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Flexible wearable electronics for cardiovascular monitoring from surface signals to deep physiological insights

FlexMat, EarlyView.
This review organizes flexible wearable electronics for cardiovascular monitoring into four interconnected information layers: surface electrophysiology, hemodynamic sensing, vascular imaging, and biofluid biomarker analysis. This framework clarifies how electrical rhythm, vascular loading, structural and flow‐related features, and biochemical states ...
Qiao Chen, Hongwen Chen, Yuanyuan Li, Pingan Yang, Rui Li, Zhihao Zhou   +5 more
wiley   +1 more source

Using different methods to evaluate the efficacy of olmesartan medoxomil in Chinese patients with mild to moderate essential hypertension according to ambulatory blood pressure monitoring

, 2012
Objective To evaluate the efficacy of olmesartan medoxomil in Chinese patients with mild to moderate essential hypertension using different methods according to ambulatory blood pressure monitoring.
Sun, Ning-ling, Hou, Ming-wei, Zhu, Jun-ren, Jiang, Hong, Wang, Ji-guang, Ke, Yuan-nan   +5 more
core   +1 more source

Pharmacokinetics and Safety of 1 mg Oral Minoxidil Tablets in Healthy Female Volunteers: A Phase I Randomized Crossover Clinical Trial

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Topical minoxidil is a first‐line treatment for female androgenetic alopecia (FAGA); however, its twice‐daily application, potential for scalp irritation and impact on hair texture can compromise adherence. Although low‐dose oral minoxidil has emerged as a promising alternative, standardized formulations with well‐characterized ...
Dolores Ochoa Mazarro, Ignacio Galicia, Ana López‐Ballesteros   +2 more
wiley   +1 more source

Association between walking gait biomechanical changes after anterior cruciate ligament injury or reconstruction and the development of osteoarthritis: A systematic review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Anterior cruciate ligament (ACL) injury and reconstruction significantly increase the risk of knee osteoarthritis (OA). Biomechanical alterations during walking are frequently suggested contributors to OA development. This systematic review aims to determine the association between walking gait biomechanical changes following ACL ...
Jérôme Riera, Mattéo Campion, Thomas Néri, Alexandre J. M. Rambaud, Noémie C. Duclos   +4 more
wiley   +1 more source

Effects of angiotensin-converting enzyme gene polymorphism and serum vitamin D levels on ambulatory blood pressure measurement and left ventricular mass in Turkish hypertensive population

, 2007
Regulation of angiotensin converting enzyme (ACE) and angiotensin II (ang-II) levels is under genetic control. 1,25(OH)2 vitamin D3 treatment has been shown to reduce the ang-II level, reduce myocardial hypertrophy and to decrease blood pressure.
Murat Can, Eyup Kulah, Mustafa Aydin, Aydin Dursun, Erol Aktunç, Serefden Acikgoz, Ahmet Dursun   +6 more
core   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus, Piort Gajewski, Piotr Ponikowski   +2 more
wiley   +1 more source

The relationship between 24 hr. central ambulatory blood pressure and arterial stiffness

, 2019
Access to thesis permanently restricted to Ball State community only.The relationship between blood pressure and arterial stiffness is complex and remains incompletely understood. This study aimed to examine the relationship between 24 hr.
Martin, Elizabeth J.
core  

Prognostic value of the morning blood pressure surge in 5645 subjects from 8 populations.

, 2010
Previous studies on the prognostic significance of the morning blood pressure surge (MS) produced inconsistent results. Using the International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcome, we analyzed 5645 subjects (mean
Kawecka Jaszcz K, International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes Investigators, Hansen TW, Metoki H, Nikitin Y, Wang J, Boggia J, Ibsen H, CASIGLIA, EDOARDO, Richart T, Stolarz Skrzypek K, Sandoya E, TIKHONOFF, VALERIE, Torp Pedersen C, Li Y, Staessen JA, Thijs L, Kuznetsova T, Imai Y, Kikuya M, Ohkubo T, Malyutina S   +21 more
core   +1 more source

Lower Urinary Tract Symptoms as Diagnostic Clues in Parkinsonism: A Practical Framework for Neurologists

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Saar Anis, Omer Anis, Abhishek Lenka, Junaid H. Siddiqui   +3 more
wiley   +1 more source