Results 61 to 70 of about 134,991 (352)

Case report: use of a cuffless blood pressure monitoring device compared to ambulatory blood pressure monitoring in a pregnant patient

Blood Pressure
Background Blood pressure (BP) monitoring is crucial for the management of hypertensive disorders of pregnancy. Cuffless, continuous BP-monitoring devices have been developed, but have yet to be validated during pregnancy.Objectives To describe the case ...
Natacha Gassmann, David Jaques, Théodore Pasquier, Bénédicte Le Tinier, Belen Ponte, Anne Dufey Teso   +5 more
doaj   +1 more source

A Unifying Theory of Biological Function [PDF]

, 2017
A new theory that naturalizes biological function is explained and compared with earlier etiological and causal role theories. Etiological theories explain functions from how they are caused over their evolutionary history.
A Gordus, A Moreno, A Wouters, AA Faisal, B Brembs, B Nanay, C Boorse, C Boorse, DC Dennett, DJ Buller, DJ Kiviet, DM Walsh, DM Walsh, J Bigelow, J Garson, J. H. van Hateren, JH Hateren van, JH Hateren van, JH Hateren van, JH Hateren van, JH Hateren van, JM Gray, K Neander, K Neander, L Wright, M Mossio, M Perlman, M Perlman, P McLaughlin, PE Griffiths, PW Glimcher, R Cummins, R Cummins, RG Millikan, RG Millikan, RM Macnab, RS Galhardo, TT Hills   +37 more
core   +4 more sources

Pain detection with bioimpedance methodology from 3-dimensional exploration of nociception in a postoperative observational trial [PDF]

, 2020
Although the measurement of dielectric properties of the skin is a long-known tool for assessing the changes caused by nociception, the frequency modulated response has not been considered yet.
Copot, Dana, Ghita, Maria, Ghita, Mihaela, Ionescu, Clara-Mihaela, Neckebroek, Martine   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Additional applications of intraoperative cerebral oxygenation monitoring using near infrared spectroscopy. [PDF]

Pediatric Anesthesia and Critical Care Journal (PACCJ), 2016
One of the major goals of intraoperative care is the maintenance of adequate cardiac output and delivery of oxygen to the tissues. Standard intraoperative monito- ring includes the non-invasive measurement of blood pressure (NIBP) and the use of pulse ...
E. Dewhirst, M. Hakim, J. D. Tobias
doaj   +1 more source

Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London [PDF]

, 2016
BACKGROUND: Anaesthesia is frequently complicated by intraoperative hypotension (IOH) in the elderly, and this is associated with adverse outcome. The definition of IOH is controversial, and although management guidelines for IOH in the elderly exist ...
Highton, D, Martin, D, Pan London Perioperative Audit and Research Network (PLAN), Wickham, A   +3 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Study Protocol for a Stepped-Wedge Randomized Cookstove Intervention in Rural Honduras: Household Air Pollution and Cardiometabolic Health [PDF]

, 2019
Growing evidence links household air pollution exposure from biomass-burning cookstoves to cardiometabolic disease risk. Few randomized controlled interventions of cookstoves (biomass or otherwise) have quantitatively characterized changes in exposure ...
Africano, Sebastian, Benka-Coker, Megan L., Brook, Robert, Clark, Maggie L., Good, Nicholas, Keller, Joshua P., L\u27Orange, Christian, Nelson, Tracy L., Osorto Pinel, Anibal, Peel, Jennifer L., Quinn, Casey, Rajkumar, Sarah, Volckens, John, Walker, Ethan S., Weller, Zachary D., Young, Bonnie N.   +15 more
core   +1 more source

Implantable devices for heart failure monitoring: the CardioMEMS™ system. [PDF]

, 2019
Several devices have been developed for heart failure (HF) treatment and monitoring. Among device-based monitoring tools, CardioMEMS™ has received growing research attention.
Abraham, Abraham, Abraham, Abraham, Abraham, Adamson, Adamson, Adamson, Adamson, Afari, Andrew Js Coats, Angermann, Bourge, Christiane Angermann, Conraads, Giuseppe Rosano, Hindricks, Hussein, Ilaria Spoletini, Landolina, Maurizio Volterrani, Ponikowski, Schmier   +22 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source