Results 61 to 70 of about 4,284,672 (297)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Association Between Blood Pressure Variability and Cerebral Small-Vessel Disease: A Systematic Review and Meta-Analysis [PDF]

, 2021
Background-—Research links blood pressure variability (BPV) with stroke; however, the association with cerebral small-vessel disease (CSVD) remains unclear. As BPV and mean blood pressure are interrelated, it remains uncertain whether BPV adds additional
Vincent, Andrew D, Tzourio, Christophe, Kario, Kazuomi, Claassen, Jurgen A H R, Tully, Phillip J, Mooijaart, Simon P, Launer, Lenore J, Lattanzi, Simona, Nagai, Michiaki, Yano, Yuichiro   +9 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

European Society of Hypertension guidelines for blood pressure monitoring at home: a summary report of the second international consensus conference on home blood pressure monitoring [PDF]

, 2008
This document summarizes the available evidence and provides recommendations on the use of home blood pressure monitoring in clinical practice and in research. It updates the previous recommendations on the same topic issued in year 2000. The main topics
Parati, G., Kario, K, Mengden, T, Waeber, B., Ruilope, L.M., Padfield, P., Staessen, Jan A., Bilo, G., de Leeuw, P., Stergiou, G S, Palatini, P., Redon, J., Mancia, G., Ohkubo, T, Shennan, A., Redon, J, Shennan, A, Asmar, R., Padfield, P, Asmar, R, Ruilope, L M, Waeber, B, O'Brien, E., Zanchetti, A., de Leeuw, P, Bilo, G, Ohkubo, T., Imai, Y., Stergiou, G.S., Lurbe, E, Zanchetti, A, Mancia, G, Manolis, A, Staessen, J A, Imai, Y, Staessen, J.A., Pickering, T., Tisler, A, Kario, K., Manolis, A., Palatini, P, Mengden, T., Revera, M, Parati, G, Pickering, T, Lurbe, E., Tisler, A., O'Brien, E, Revera, M.   +48 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk [PDF]

, 2011
Blood pressure is a heritable trait1 influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension ($140mmHg systolic blood pressure or$90mmHg diastolic blood pressure)2. Even small
Harst, P. (Pim) van der, Lawrence, Robert W, Sinning, Christoph, Wichmann HE, Preuss, M., Ridker, P.M., Wilensky R, Launer, L, Assimes, Themistocles L., Go, Alan, Heid, I. M., Ingelsson, E., Elosua, R., Fava, C. (Cristiano), Staessen, J.A. (Jan), Kim, HL, Boerwinkle, E., Dong, Y., Prabhakaran, D, van der Schouw, Y.T., Hicks, Andrew A, Ongen, H. (Halit), Palmer, L.J., Langefeld, C.D. (Carl), Hengstenberg, Christian, Wichmann, H. Erich, Kangas, Antti J., Glazer, NL, Shin Cho, Y. (Yoon), Smith, Nicholas, Peters, Annette, Tayo, B. (Bamidele), Young, J. Hunter, Smith, AV, Day, I.N.M., Lathrop, Mark, Steinle, NI, Stančáková, A, Curhan, G. C., Dong, YB, Preuss M, Cooper, Richard S, Glazer, N., Kuznetsova, T, Barroso, Inês, Ong, R.T., Lawrence, Robert W., O´Connell, J.R., Forrester, T, Corsi, A.M. (Anna Maria), Vinay, D G, Chambers, John C, Tomaszewski, M, Palmer, Lyle J., O'Donnell, CJ, Frayling, Timothy M., Nilsson, Peter M., Wichmann, H.E. (Heinz Erich), Floege, J., Seielstad, M, Hwang, S. J., Roberts, Robert, Igl, W., Harris, T.B. (Tamara), Knowles, J., Ongen, Halit, Voelker, Uwe, Quertermous, T., Seielstad, Mark, Heckbert, Susan R., Lee, NR, Miki, T., Johnson, A.D. (Andrew), Li, Mingyao, Nilsson, P. (Peter), Munroe, PB, Kong, A., Ong, RT, Schillert, A., Perret, Claire, Ludwig, Barbara, Thorgeirsson, G., Milaneschi, Y. (Yuri), Smith, GD, Rivadeneira, F, Turner, S. T., Chang, Yen-Pei C, Bilo, H. J., Sidney, Steven, Fava, Cristiano,, Salako, T., Iwai, N., Lackner, K., Strachan, David P., Schreiber, S., Morris, R.W. (Richard), Ohkubo, T, Johnson, T, Ong, RTH, Nelson C, Sinning C, Bolton, J.A.H., Chen L, Wu, Fenny, Rudan, I. (Igor), König, I. R., Winkelmann, B.R., Orru, Marco, Järvelin, M.-R., Najjar, S., Nicaud, Viviane, O’Donnell, Christopher J., Tripathy, Vikal, Uitterlinden, Andre G, Braund, Peter S., van Gilst, WH, Smith, A.V. (Albert Vernon), Quertermous T, Völker, U. (Uwe), Fortmann, Stephen, Knouff, C.W., Zillikens, M. C., Sternberg, M. J., Rice, K.M., Zhang, W., Illig T, Levy, D. (Daniel), Taylor, K.D., Gyllensten, Ulf B, Andersen, K., Mani, K Radha, Milaneschi, Y, Raitakari, Olli T., Vitart, Veronique, Völzke, H. (Henry), Emilsson, V., Hercberg, S., Iribarren, Carlos, Nguyen, Khanh-Dung Hoang, Waterworth, Dawn M., Lucas, Gavin, Cupples, L.A., Kähönen, M., Loley, Christina, Cavalieri, M., Dominiczak, Anna F, Wright, A.F., van der Schouw, YT, Gao, X., Hadley, D., Sijbrands, Eric J.G., Burtt N, Talmud, P.J., Hakonarson, H.H., et al, Kangas, AJ, Gale, D. P., Graessler, J, Wareham, N.J., Scharnagl H, Li, Y., de Faire, Ulf, Longstreth Jr., W.T., Wild, S.H. (Sarah), Heath, S., Weder, A.B. (Alan), Erdmann, Jeanette, Gabriel SB, Zhu, H. (Haidong), Artigas, M.S., Dehghan A, Stancáková, A. (Alena), Illig, T., Soininen, P. (Pasi), Galan, P., Li, YL, Yang, Q., van Gilst, Wiek H, Zhang, WH, Swift, A.J. (Amy), Vineis, P., Hicks, Andrew A., Brand, Stefan Martin, Tai, E Shyong, Jackson, A.U., Knouff, Christopher W., Hoffmann M, Wilson, James F, Whincup, P.H., Wong, TY (Tien Yin), Longstreth Jr, W. T., Org, E, Bornstein, SR, KidneyGen Consortium, Völzke, H, Parker, AN, Wagenknecht, Lynne E., Wass, M. N., Schillert A, Witteman, Jacqueline C.M., Kroemer, H. K., Wu, Y, Hofman A, Guarrera, S, Köttgen, Anna, Chen, I.Y., Dobnig H, Erdmann, J, Adeyemo, A. (Adebowale), Nelson, C., Wright, AF, Boban, M., Larson, Martin G., Najjar, Samer S., Meschia, James F, Farrall, M. (Martin), Hercberg, Serge, Palmer, LJ, Kooner, J.S. (Jaspal), Parker, A. N., Beckmann, Jacques S, Hicks, A.A., Sijbrands, EJ, ICBP Consortium (Meitinger, T. ; Wichmann, H.-E. ; Gieger, C.), Hua Zhao, Jing, Brand, Eva, Waterworth, D., Melander, O, Qu, Liming, Polasek, Ozren, Miki, T, Grässler, J., Medack A, Shriner, D, Chang, Yen-Pei C., Snieder, H. (Harold), Uiterwaal, C.S.P.M., Salomaa, V. (Veikko), van Duijn, Cornelia M., Sehmi, J.S., Zerres, K., Mosley, Thomas H., Kao, WHL, Psaty, B. M., Groop, L. (Leif), Lakatta, Edward G., Ehret, Georg B, Heckbert, S. R., Renner W, Sõber, S. (Siim), Terzic, J. (Janos), Bakker, S.J.L. (Stephan), Jackson, Anne U, Newton-Cheh, C, Ikram, Arfan, Snieder, Harold, Grobbee, D.E. (Diederick), Marciante, Kristin, Struchalin, M., Gabriel, Stacey B., Fowkes, F. Gerald R., Palmas, W, Collins, FS, Lumley, Thomas, Fowkes, F.G.R., Kim, Hyung Lae, Janipalli, C.S., Hernandez, Dena, Zhao, JH, Kumar, M. V. Kranthi, Kuusisto, J. (Johanna), Laakso, M. (Markku), Shrine, N.R., Kivimaki, M., Chen, M.H., Longstreth, W. T., Jr., Chang, Y.-P.C. (Yen-Pei), Langefeld, Carl D., Pramstaller, PP, Hoang Nguyen, KD, Uiterwaal, CSPM, Greiser, K. H., Vollenweider, P, Smith, A., Najjar, S.S. (Samer), Rotimi, C, Halperin, Eran, Coresh, J., Ala-Korpela, M. (Mika), Barroso, I.E. (Inês), Zhu, Haidong, Elliott, P., Fuchsberger, C., Prabhakaran, Dorairaj, Palmas, W., Hilton, Gina, Demissie, Serkalem, Whincup, Peter H., Tanaka, T, Humphries, S.E. (Steve), Cupples LA, Steinle, Nanette I., Hwang, S-J, Psaty, Bruce M., Salako, Tunde, Onland-Moret, N.C. (Charlotte), Jarinova, O., Mägi, R., Vinay, D. G., Beilby, John P, Smith, N.L., Elosua, Roberto, Demirkan, A, Tuomilehto, J., Zhai, G. (Guangju), Swift, Amy J, Galan, P, Köttgen, A., Morrison, Alanna C, Hoffmann, Michael M., Arfan Ikram, M., Uiterwaal, CS, Walker, M.C., Gaunt, Tom R., Deloukas, P, Launer, L. J., Ehret, G.B., Prabhakaran, D., Lakatta, EG, Krämer, B. K., Holm H, Bis, J.C. (Joshua), Franke, A., Cooper, Jackie A., Chasman, D.I. (Daniel), Lieb, W., Mohlke, K.L., Campbell, Harry, Teumer, A. (Alexander), Garcia, Melissa E, Voight, Benjamin F, Lyytikäinen, L.-P., Pichard AD, Scott, J., Ellinghaus, D., Mattace-Raso, Francesco U.S., McKenzie, C.A., Lyytikainen, L-P, Bochud, M., Hlatky M, Bergmann, S, Plump, A., Tang, Hua, Lawrence, RW, Medack, A., Parsa, A., Khaw, KT, Hartikainen, AL, Schnabel R, Talmud, Philippa J., Hoffman Bolton, Judith A., Grosshennig A, Heckbert, Susan, Yajnik, C.S., Charchar, Fadi J., Heckbert, S.R. (Susan), Satler, Lowell, Rotter JI, Hernandez, D.G. (Dena), Erdmann, J. (Jeanette), Chasman, DI, Adeyemo, A, Zhu, H, Smith, G.D., Denniff, M. (Matthew), Absher D, Matthai, W., Doering, Angela, Young, J Hunter, Rao, Dabeeru C., Thompson, J.R., Zelenika, D, Mattace-Raso, Francesco U S, Alexander, Myriam, Zhu, X, Lathrop, G.M. (Mark), Li, M., Langefeld, C.D., Bots, ML (Michiel), Kangas, A.J. (Antti), Bis, J.C., Wilson, J.F., Doumatey, Ayo P., Samani, N.J., Meisinger C, Okamura, Tomonori, Kent, K.M., Kathiresan, S, Rader, Daniel J., Schwartz, S.M. (Stephen), Raitakari, O., Friedrich, N., International Consortium for Blood Pressure Genome-Wide Association Studies, Platou, C. (Carl), Connell, J. M., Samani NJ, Beilby, JP, Palmer, ND, Wong, Tien Y, Knowles, Joshua, Howard, P, Soranzo, N., Adair, LS, Schmidt, H., Epstein, S., Waeber, G., Pouta, A., Rotter, J. I., Perola, M. (Markus), Wichmann, HE, Day, Ian N.M., Preuss, Michael, Brand, E (Eddy), Isaacs, A., Kardia, Sharon L. R., Homan van der Heide, J. J., Chang, Y-PC, Arnett, D. K., Hwang, S.J., Brand, E, Burton, P.R. (Paul), Wilson, James F; id_orcid, Corsi, Anna Maria, O'Reilly, P.F., Bergmann, S., Voelker, U, Völker, U., Rettig, R. (Rainer), Kuh, D, Bickel, Christoph, Frayling, Timothy M, Farrall, M., Teumer, Alexander, Umemura, S., Matullo, G., Dominiczak, Anna F., Demirkan, A. (Ayşe), Wells, G.A., Ehret, Georg B., Laan, M, Emilsson, Valur, Zelenika, D. (Diana), Aulchenko, Yurii S., Cupples, L. Adrienne, Bakker, Stephan J.L., Peden, John F., O’Reilly, Paul F., Lakatta, Edward G, Vasan, RS, Beckmann, J.S. (Jacques), Lawlor, D. A., Loehr, Laura R., Prokopenko, I, Kuznetsova, T. (Tatiana), Chambers, J.C., Khaw, Kay-Tee, Viigimaa, M., Day, I.N., Raffel, Leslie J, Sijbrands, E.J.G. (Eric), Taylor, A., Schlieper, G., van der Schouw, Yvonne T., Ganesh, Santhi K, Samani, Nilesh J, Peltonen, L. (Leena Johanna), Kardia, S.L., Tomaschitz A, Rodeheffer, R. J., McArdle, W.L., Melander, O., Parsa, A. (Afshin), Cooper, J.A., Wong, T.Y., Zitting, P. (Paavo), Sidney, S., Fox, E.R. (Ervin), Gretarsdottir, Solveig, Khanh-Dung Hoang, Nguyen, Hayward, Caroline, Hofman, A. (Albert), Nahrstedt, J., Erdmann J, Ohkubo, T., Voight, B.F., Igl, Wilmar, Steinle, N.I. (Nanette), Wild, S. H., Lackner, K. J., CARDIoGRAM Consortium, Kroemer, H.K., Ala-Korpela, Mika, Caulfield, MJ, Haritunians, T., Coresh, J, Fowkes, FGR, Rasheed, A. (Asif), Balmforth AJ, Schmidt, R., Winkler K, Kooner, JS, McKenzie, Colin A., Hicks, AA, Kuusisto, Johanna, Aspelund, T, Chang, Y.-P.C., Mattace-Raso, FU, Adeyemo, A., Morris, Richard W, Lakatta, E.G., International Consortium for Blood Pressure Genome-Wide Association Studies,, Dreisbach, A.W., Oostra, B.A., Emilsson, V, Watkins, Hugh, Freyer, J., Shi, G. (Gang), Kulkarni, SR, Thelle, Dag S, Morken, Mario A, Fowkes, F.G.R. (Gerald), Jafar, T.H., Ramachandran, Vasan, O'Reilly, P.F. (Paul), Renner, Wilfried, Viigimaa, Margus, Saleheen, Danish, Spector, T.D., Sijbrands, E.J., Loos, R.J.F., Kinra, S, Howard, P., Sjögren, Marketa,, Scott, LJ, Gulde, Stephanie, Kathiresan, Sekar, Rice, Kenneth M, Larson, Martin G, Wilson, JF, Gyllensten, U.B., Han, B.-G., Kardia, S.L. (Sharon), Holm, H., Abecasis, G. R., Lohman, Kurt K., Aulchenko, Yurii, Rupprecht HJ, Arora, P., Bots, Michiel L., Münzel T, Absher, D., Alexander, M. (Myriam), Hwang, Shih Jen, Kulkarni, S.R., Aulchenko, Yuriy, Gaunt, Tom R, Wilson, J.F. (James), Wong, TY, Sõber, Siim, Meitinger, T. (Thomas), Wain, Louise V, Bickel C, Grosshennig, A., Cooper, M.N. (Matthew), Zukowska-Szczechowska, E., Hopewell, J.C., Barbalic M, McPherson, R., Ikram, M.A. (Arfan), Palmen, J., Barroso, Ine S., Lee, JY, Wagenknecht, L.E. (Lynne), Lackner, Karl, Hlatky, M., Vartiainen, E., Uda, M., Danesh, J, Weder, Alan B., Rivadeneira Ramirez, F. (Fernando), Connell, J.M., Linsel-Nitschke, P., Wong, Tien Y., Böhm BO, Harris, Tamara B, Watzinger, N., Morrison, A.C. (Alanna), Kathiresan, S., Okamura, T. (Tomonori), Ong, Rick Twee Hee, Kettunen, Johannes, Bickel, C., Campbell, H. (Harry), Caulfield, M. (Mark), Groop, L, Boehnke, M, Walker M, Wichmann, H.-E., Kathiresan S, Folsom, A., Willenborg, C., Shi, Gang, Knowles J, Chen, Ming Huei, Zhu, H., van Duijn, C. M., Peltonen, L, Humphries, S.E., Kita, Y, Sidney S, Kao, W.H.L., Blankenberg, Stefan, Levy D, Cooper, Matthew N, Zhu, HD, Melander, Olle,, Peden, J. (John), Kumari, M. (Meena), Terzic, J., Whincup, PH, Swift, A.J., Ueshima, H. (Hirotsugu), Thorgeirsson, Gudmundur, Tayo, B., Sehmi, J. S., Demirkan, A., Bochud, Murielle, Doumatey, A, Nalls, Michael A., Humphries, Steve E, Parker, A.N. (Alex), Ebrahim, S., Hveem, K., Longstreth, W T, Kong, Augustine, Taylor KD, Mooser, Vincent, Uitterlinden, AG, Heckbert, Susan R, Orru, M., Gieger, C, Kumar, MV, Pichard, A.D., Harris, Tamara, Laaksonen, R., Levy, Daniel, Wiggins, K.L. (Kerri), Khaw, K-T. (Kay-Tee), Wichmann, H-Erich, Tobin, M.D. (Martin), Burnett, Mary Susan, Cooper, RS, Goel, Anuj, Wong, A., Dockrell, M., Watkins, H., Aspelund, T. (Thor), Thelle, Dag S., Vineis, Paolo, Schlessinger, D., Roberts R, Narisu, N., Lindsay, J.M., Platou, C.G.P., Chang, YPC, Andersen K, Ueshima, Hirotsugu, van Duijn, CM, Lee, J.Y., Nauck, M., Lawrence, R.W. (Robert), Bakker, Stephan J. L.; id_orcid, Langefeld, CD, Bots, Michiel L, Campbell, Harry; id_orcid, Longstreth jr., W. T., Wiggins, K.L., Kuznetsova, Tatiana, Meschia, JF, Ferrucci, L. (Luigi), Chasman, Daniel I, Kumar, M V Kranthi, Kolcic, I., Sõber, S, Singleton, Andrew, Ridker, P. M., Johnson, T., van Duijn, C., Salomaa, V, Sjögren, M, Kinra, S. (Sanjay), Hveem, K. (Kristian), Lumley T, Shuldiner, A.R., McKenzie, CA, Han, BG, Rudock, M.E., Paré, G., Soranzo, N. (Nicole), Seshadri, S., Platou, C.G., Hilton, G., Brown, MJ, Lagou, V., Halperin, E., Vineis, P. (Paolo), Wiggins, Kerri L, Province, M., Uda, Manuela, Ricceri, F. (Fulvio), Prokopenko, Inga, Marciante, K., Parker, Alex N., Harris T, O'Donnell CJ, Ikram, M Arfan, Felix, J. F., Snieder, H, Bergmann, Sven, Lawlor, Debbie A., Launer, Lenore J., Fox, C. S., Bergmann, S.M. (Sven), Wichmann, H. E., Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Adair, L.S., Hingorani, Aroon D., Rotimi, C. (Charles), Scuteri, A., König IR, Luan, Jian’an, Kleber, Marcus, Dreisbach, Albert W, Ueshima, H., Raffel, L.J. (Leslie), Rotter, Jerome I, Marmot, MG, Badola, S., Kuh, D., Hengstenberg C, Cambien, F., Dikkeschei, L. D., Goel, A., Bornstein, S.R. (Stefan), Thompson, John R., Walker, Max C., Risch N, Kim, H-L, Stojakovic, Tatjana, Hunt, Steven C, Terzic, Janos, Erdmann, J., Arora, Pankaj, Aulchenko, Y. S., Laitinen, J, Wagenknecht, Lynne E, Janipalli, CS, Chambers, J. C., Sjögren, Marketa, Fowkes, F.G., Raffel, L.J., Absher, Devin, van der Harst, Pim, Adeyemo, Adebowale, Perucha, E., Lucas, G. (Gavin), Palmer, Nicholette D., Sun, Yan V, Corsi, A.M., Schwarz, P.E., Tobin, Martin D, Jarinova O, Sun, Yan V., Artigas, Maria Soler, Nguyen, KD, Homuth, G., Maxwell, P. H., Dobnig, H., Onland-Moret, Charlotte N, Gretarsdottir, S., Jafar, T.H. (Tazeen), Uitterlinden, A. G., Sharma, P. (Pankaj), Mooser, V. (Vincent), Shaw-Hawkins, S. (Sue), Loley C, Koettgen, A, Guarrera, Simonetta, Wain, L.V. (Louise), Beckmann, J.S., Zgaga, L., Bolton, Judith A Hoffman, Stenvinkel, P., Kinra, Sanjay, Chambers, John C., Dahgam, S, Polasek, O., Lohman, Kurt K, Würtz, P., Kullo, I., Uitterlinden, A., Kumar, MV Kranthi, Brand, S-M, Kita, Yoshikuni, Morrison, Alanna, Collins, Francis S., Schunkert H, Iwai, N, Nalls, Michael A, Harris, TB, Wu, Y., Casas, Juan P., Deloukas, Panos, Pilz S, Ohkubo, Takayoshi, Harris, T., Shrine, Nick RG, Wareham, Nicholas J., Dahgam, S. (Santosh), O'Connell, J.R., Sim, X. (Xueling), Saleheen, D., Stewart, A.F., Arking, Dan E., Laitinen, Jaana, Brand, S.-M., Bakker, S. J., Abecasis, GR, Oostra, B.A. (Ben), Wang, TJ, Maria Corsi, Anna, Go, Min Jin, Kardia, Sharon L., Burtt, Noel, Ludwig, B, Zhao, J.H., Cooper, Jackie A, Vitart, V, Larson, M.G., Shaw-Hawkins, S, Fortmann S, Hayward, C, Waterworth DM, Mattace-Raso, F.U., Chen IY, Wang, X., Seelen, M. A., Gyllensten, U. (Ulf), Strachan, DP, Vasan, R.S., Böhm, Bernhard O., Lakatta, E. (Edward), Glazer, N.L., Kettunen, J, Cooper, R.S., Bornstein, Stefan R., Spector, TD, Vineis, P, Taylor, A. (Andrew), Tang, H., Wang, W., Tukiainen, Taru, Sehmi, Joban S., Milaneschi, Y., Wichmann, H. -Erich, Ferrucci, L., Nelson, Chris, Connell, JM, Hartikainen, A.L., Oostra, B. A., Hveem, Kristian, Bis, J. C., Forrester, T. (Terrence), Dahgam, Santosh, Munzel, T. F., Raffel, Leslie J., Denniff, Matthew, Lee, N.R. (Nanette), Isaacs, A, Zhu, XF, Tabara, Y, Peden, JF, Uda, M. (Manuela), Lehtimäki, T, Sim, Xueling, Strachan, David P, Shi, G., Mitchell, G. F., Tiret L, Guarrera, S., Abecasis, G.R. (Gonçalo), Winkler, Karl, Vasan, R. S., Spector, T. D., Radha Mani, K., Altshuler D, Samani, Nilesh J., Platou, CGP, Campbell, H, Bakker, Stephan J. L., Marciante K, Hofman, Bert, Wright, A. F., Nguyen, K.D., Gulcher, Jeffrey R., Burton, Paul R., Hunt, SC, Hercberg, S. (Serge), Watkins, H, Chang, YP, Bolton, Judith A. Hoffman, Ferrucci, Luigi, Zhu, X., Kardia, Sharon L, Kumar, M.V., Pichard, Augusto D., Spector, Tim D., Olden, M, Sijbrands, Eric J G, Olden, M., Gansevoort, R. T., Snieder, H., Wang, Xiaoling, Nitsch, D., Nicaud V, Arking, D.E. (Dan), Day, IN, Wichmann, H.-Erich, Shriner, D. (Daniel), Kleber M, Gaunt, TR, Ricceri, F., Khaw, K-T, Stark, K., Charlotte Onland-Moret, N., Meneton, Pierre, Khaw, K.-T., Smith, N. L., Hakonarson, Hakon H., Würtz, Peter, Gieger, C., Umemura, S. (Satoshi), Kleber, M., Pihur, Vasyl, Verwoert, G.C. (Germaine), Ridker, Paul M, Artigas, MS, Redfield, M. M., Lyytikäinen, LP, Elliott, P. (Paul), O'Donnell, Christopher J., Jarvelin, M-R, Wild, Philipp, Rice, K.M. (Kenneth), Lawlor, DA, Altshuler, D, Clarke, Robert, Miki, Tetsuro, Seielstad, M. (Mark), Hartikainen, Anna Liisa, Chambers, JC, Coresh, J. (Josef), Waterworth, D.M., Olden, M. (Matthias), Mangino, Massimo, Hicks, A.A. (Andrew), Verwoert, Germaine, Lucas, G, Hadley, D, Wild, S.H., Miki, T. (Tetsuro), Palmas, W. (Walter), Clarke, R., Rudock, Megan E., Sim, X, Fava, Cristiano, de Andrade, M., Mosley, TH, Swaminathan, R., Werdan, K., Hamsten, A. (Anders), Zhai, Guangju, Stefansson, K., Eiriksdottir, G., Würtz, P, Tiret, L., Johnson, AD, Siscovick, D., Wilde, S.   +999 more
core   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source