Results 51 to 60 of about 5,572,201 (259)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure [PDF]

Introduction: Blood pressure (BP) is a highly heritable trait with over 2000 underlying genomic loci identified to date. Although the kidney plays a key role, little is known about specific cell types involved in the genetic regulation of BP.Methods ...
de Borst, Martin, International Consortium of Blood Pressure; Soroush Sardari, de Borst, M, Koskinen, Seppo, Sardari, S, Vaez, A, International Consortium of Blood Pressure, de Borst, Martin; id_orcid, Snieder, H, Gow, Alan J.; id_orcid, Snieder, Harold, ?, ?, Kamali, Z, Ganji-Arjenaki, M, Ganji-Arjenaki, Mahboube, Snieder, Harold; id_orcid, Kamali, Zoha; id_orcid, Sardari, Soroush, Vaez, Ahmad, Vaez, Ahmac, et al., Kamali, Zoha   +21 more
core   +1 more source

Reliability of beat-to-beat blood pressure variability in older adults

Scientific Reports
Blood pressure variability (BPV) is emerging as an important risk factor across numerous disease states, including cerebrovascular and neurodegenerative disease in older adults.
Trevor Lohman, Isabel J. Sible, Fatemah Shenasa, Allison C. Engstrom, Arunima Kapoor, John Paul M. Alitin, Aimee Gaubert, Julian F. Thayer, Farrah Ferrer, Daniel A. Nation   +9 more
doaj   +1 more source

MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE

Рациональная фармакотерапия в кардиологии, 2015
Nowadays conception of blood pressure (BP) variability (BPV) includes a number of indicators related to various physiological factors. All the indexes are calculated with the standard deviation (SD) or more complex formulas, including SD.
V. M. Gorbunov
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Blood pressure variability — 15 years later

Рациональная фармакотерапия в кардиологии
Blood pressure variability (BPV) has been studied for a long time, and recently important new information has been obtained about the prognostic value of BPV and the influence of antihypertensive therapy on it.
V. M. Gorbunov, E. V. Platonova
doaj   +1 more source

The Paraventricular Nucleus of the Hypothalamus in Control of Blood Pressure and Blood Pressure Variability

Frontiers in Physiology, 2022
The paraventricular nucleus (PVN) is a highly organized structure of the hypothalamus that has a key role in regulating cardiovascular and osmotic homeostasis.
Bojana Savić, David Murphy, Nina Japundžić-Žigon   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source