Results 71 to 80 of about 5,572,201 (259)

Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients

Clinical and Experimental Hypertension, 2018
The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed
Minako Inoue, Kiyoshi Matsumura, Yoshie Haga, Yasuo Kansui, Kenichi Goto, Toshio Ohtsubo, Takanari Kitazono   +6 more
doaj   +1 more source

Effect of citicoline on blood pressure variability

Неврология, нейропсихиатрия, психосоматика, 2014
The authors give the results of their investigation dealing with citicoline therapy in patients with hypertension and cognitive impairments.Objective: to determine the efficiency of citicoline therapy on the level and variability of both systolic and ...
O. D. Ostroumova, N. Yu. Taranenko
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Dysglycemia induces abnormal circadian blood pressure variability

Cardiovascular Diabetology, 2011
Background Prediabetes (PreDM) in asymptomatic adults is associated with abnormal circadian blood pressure variability (abnormal CBPV). Hypothesis Systemic inflammation and glycemia influence circadian blood pressure variability.
Kumarasamy Sivarajan, Gopalakrishnan Kathirvel, Kim Dong Hyun, Abraham Nader G, Johnson William D, Joe Bina, Gupta Alok K   +6 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion [PDF]

, 2009
WNK1 - a serine/threonine kinase involved in electrolyte homeostasis and blood pressure (BP) control - is an excellent candidate gene for essential hypertension (EH). We and others have previously reported association between WNK1 and BP variation. Using
Kumari, Meena, Hoti, Mimoza, Samani, NJ, Peeter Juhanson, Elliott Paul, C. Ji (7611359), M. Marmot (7611368), Anna F Dominiczak, Juhanson, P, Marmot, Michael, Connell, JM, Philip Howard, Shaw Hawkins, Sue, Kumari Meena, P. B. Munroe (7602386), J. Chambers (3846385), Veldre, G, Farrall, Martin, Connell John M., Pasquale Strazzullo, John Chambers, Marmot Michael, Dobson, R, Kumari, M, Burke, Beverley, Samani Nilesh J., Brown, M. J. (Morris Jonathan), Morris Brown, Newhouse, Stephen; id_orcid, Elliott, Paul, Gudrun Veldre, Shaw-Hawkins, Sue, B. Burke (7611347), Strazzullo, P, Dobson, Richard; id_orcid, R. Collins (7159586), Iacone, Roberto, Cappuccio, Francesco P., Laan, Maris, Lathrop, G. Mark, Kooner, Jaspal, Munroe, Patricia B., Clarke, R, Beverley Burke, Brunner, Eric, P. Strazzullo (7611365), Farrall Martin, Viigimaa Margus, Brown, M, Lee, Kate, Hoti, M, Samani, Nilesh J., Francesco P Cappuccio, Newhouse Stephen, P. Howard (7611350), Richard Dobson, S. Newhouse (6642536), Juhanson Peeter, Elliott, P, Org, E, Nilesh J. Samani (7579793), Farrall, M, Burke Beverley, Lathrop G. Mark, Paul Elliott, Newhouse, S, Veldre, Gudrun, E. Org (7602644), Wallace Chris, Burke, B, Caulfield, Mark, Chambers, John, Marmot, Michael G., Martin Farrall, John M Connell, Onipinla Abiodun, Hoti Mimoza, M. Laan (7602659), Maris Laan, Dominiczak, AF, J. M. Connell (7602551), M. Viigimaa (7602620), Cappuccio Francesco P., Cappuccio, FP, Newhouse, Stephen, Onipinla, A, Kate Lee, Shaw-Hawkins Sue, Susana Eyheramendy, Iacone Roberto, Marmot, M, C. Wallace (7602467), Munroe, PB, Brown, Morris, Jaspal Kooner, Wallace, C, M. Farrall (6522599), Dominiczak Anna F., S. Eyheramendy (7611197), Roberto Iacone, Caulfield, M, Eric Brunner, Lee, K, Chris Wallace, Strazzullo Pasquale, Brunner Eric, M. Brown (3020991), G. M. Lathrop (7611353), Collins Rory, G Mark Lathrop, Juhanson, Peeter, Ji Chen, Meena Kumari, Howard Philip, Cappuccio, Francesco, Chambers, John, MD, Org, Elin, Caulfield Mark, K. Lee (1769563), E. Brunner (7611371), Lathrop, GM, S. Shaw-Hawkins (7602380), Org Elin, Chambers John, Iacone, R, Brunner, E, Margus Viigimaa, F. P. Cappuccio (7611356), Wallace, Chris, P. Elliott (1293702), Viigimaa, Margus, R. Dobson (6375266), A. F. Dominiczak (7602482), Chen Ji, Connell, John M., Connell, J. M. C., Sue Shaw-Hawkins, Dobson, Richard, Munroe Patricia B., Clarke, Robert, Eyheramendy, S, Rory Collins, Patricia B Munroe, Howard, P, M. Caulfield (7609097), Eyheramendy, Susana, Collins, Rory, Dobson Richard, Veldre Gudrun, Mimoza Hoti, Stephen Newhouse, Collins, R, M. Hoti (7611344), Laan Maris, Elin Org, Robert Clarke, Ji, C, Viigimaa, M, Shaw-Hawkins, S, Onipinla, Abiodun, Michael Marmot, Dominiczak, A. F., Mark Caulfield, R. Iacone (7611362), Abiodun Onipinla, G. Veldre (7602656), Clarke Robert, Eyheramendy Susana, A. Onipinla (7602377), M. Kumari (7602503), Kooner Jaspal, P. Juhanson (7602641), Nilesh J Samani, Dominiczak, Anna F., Lee Kate, Chambers, J, Strazzullo, Pasquale, Howard, Philip, Ji, Chen, Kooner, J, Brown Morris, J. Kooner (7609340), R. Clarke (7602407), Laan, M   +183 more
core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Blood pressure variability and stroke: A risk marker of outcome and target for intervention

The Journal of Clinical Hypertension, 2021
Simona Lattanzi, Francesco Brigo, Mauro Silvestrini   +2 more
doaj   +1 more source

Methodological insights and correlations of short-term BP variability indices

Blood Pressure
Background Blood Pressure Variability (BPV) is an independent risk factor for cardiovascular events. Short-term indices of BPV, such as standard deviation (SD), coefficient of variation (CV), average real variability (ARV), and Time Rate Index (TRI) are ...
Sandra C. Fuchs, Guilherme S. Procianoy, Marcelo B. Lucca, Leonardo K. Valter, Arthur L. Tavares, Beatriz P. Camilo, Letícia R. P. Silveira, Juliano A. Jorge, Fabio T. Cichelero, Flavio D. Fuchs   +9 more
doaj   +1 more source