Results 91 to 100 of about 847,779 (310)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Representative images of blood vessel profiles.

open access: yes, 2016
Representative images of blood vessel profiles (indicated by arrowheads) with serum extravasation (indicated by asterisk) in the subcortical white matter of a lamb that received a single 30 s sustained inflation (single SI; A) and 5 consecutive 3 s ...
Georg M. Schmölzer (444764)   +10 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

How good are the fits to the experimental velocity profiles in vivo?

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Koutsiaris, AG   +3 more
core  

Exploring MSM blood donor profiles: a descriptive analysis of demographics, risk characteristics, and donation behaviors

open access: yes
BackgroundThe importance of addressing the blood donor population among men who have sex with men (MSM) is increasing with the global liberalization of blood donor deferral policies.
Saxton, Peter   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Blood flow in microvascular networks

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
Mansour, MH   +3 more
core  

Blood doping and its detection [PDF]

open access: yes, 2011
Hemoglobin mass is a key factor for maximal exercise capacity. Some athletes apply prohibited techniques and substances with intent to increase hemoglobin mass and physical performance, and this is often difficult to prove directly.
Lundby, C   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

HERBAL METHIONINE (METHIOREP®) IMPROVES GROWTH PERFORMANCE OF BROILER CHICKENS WITHOUT AFFECTING CARCASS CHARACTERISTICS AND BLOOD INDICES

open access: yesTropical and Subtropical Agroecosystems, 2017
Methiorep®, an herbal methionine premix, which is reported to contain herbal ingredients that mimic the activity of Methionine such as SAMe (S-Adenosyl Methionine) and phosphatidyl choline, have recently introduced to Nigeria animal feed industry.
O.J. Makinde   +6 more
doaj  

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