Results 111 to 120 of about 12,332,569 (295)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Representative images of blood vessel profiles.

open access: yes, 2016
Representative images of blood vessel profiles (indicated by arrowheads) with serum extravasation (indicated by asterisk) in the subcortical white matter of a lamb that received a single 30 s sustained inflation (single SI; A) and 5 consecutive 3 s ...
Georg M. Schmölzer (444764)   +10 more
core   +1 more source

Supplemental information for: 'Associations of early pregnancy metabolite profiles with gestational blood pressure development'

open access: yes, 2022
Supplementary material for 'Associations of early pregnancy metabolite profiles with gestational blood pressure development'
Berthold Koletzko (144194)   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The effects of labor on differential gene expression in parturient women, placentas, and fetuses at term pregnancy

open access: yesKaohsiung Journal of Medical Sciences, 2011
Labor and its associated pain are thought to have unique impacts on parturient women. The goal of this study was to investigate the effects of labor and associated pain on differential gene expression profiles in the maternal, fetal, and placental ...
Hsiu-Huei Peng   +9 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Characterisation of linear predictability and non-stationarity of subcutaneous glucose profiles [PDF]

open access: yes, 2013
Continuous glucose monitoring is increasingly used in the management of diabetes. Subcutaneous glucose profiles are characterised by a strong non-stationarity, which limits the application of correlation-spectral analysis.
Holt, Tim A.   +4 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Effects of Exogenous Lysolecithin Emulsifier Supplementation on the Growth Performance, Nutrient Digestibility, and Blood Lipid Profiles of Broiler Chickens

open access: yesThe Journal of Poultry Science, 2018
This study aimed to evaluate the effects of dietary supplementation of lysolecithin emulsifier on growth performance, nutrient digestibility, and blood lipid profiles in growing broiler chickens.
Jae-Hong Park   +2 more
doaj   +1 more source

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