Results 21 to 30 of about 1,228,812 (242)

Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. [PDF]

open access: yes, 2011
The contribution of peripheral immunity to autism spectrum disorders (ASDs) risk is debated and poorly understood. Some mothers of children with ASD have autoantibodies that react to fetal brain proteins, raising the possibility that a subset of ASD ...
Ashwood, P   +4 more
core   +2 more sources

A novel mutation in NDUFB11 unveils a new clinical phenotype associated with lactic acidosis and sideroblastic anemia [PDF]

open access: yes, 2017
NDUFB11, a component of mitochondrial complex I, is a relatively small integral membrane protein, belonging to the 'supernumerary' group of subunits, but proved to be absolutely essential for the assembly of an active complex I.
Bertini, Enrico   +21 more
core   +2 more sources

Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin

open access: yeseLife, 2016
Venom toxins are invaluable tools for exploring the structure and mechanisms of ion channels. Here, we solve the structure of double-knot toxin (DkTx), a tarantula toxin that activates the heat-activated TRPV1 channel. We also provide improved structures
Chanhyung Bae   +10 more
doaj   +1 more source

Blood cells and some hematological parameters of red drum (Linnaeus, 1766) in Vietnam

open access: yesBrazilian Journal of Biology, 2021
This research focuses on hematological characteristics, erythrocyte morphology and some biochemical parameters of red drum Sciaenops ocellatus (Perciformes: Sciaenidae), cultured in natural water environment in areas near river mouth (L1), estuaries (L2)
D. H. Quyet
doaj   +1 more source

Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]

open access: yes, 2017
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo   +4 more
core   +2 more sources

Toxicological study of Zaleplon (Anxiolytic drug) in experimental animals

open access: yesZagazig Journal of Pharmaceutical Sciences, 2014
Anxiety disorders are among the most prevalent mental disorders in the general population. Nearly 30 million persons are affected in the United States, with women affected nearly twice as frequently as men.
Mostafa E. El-Naggar   +4 more
doaj   +1 more source

Activated protein C in epilepsy pathophysiology

open access: yesFrontiers in Neuroscience, 2023
Epilepsy is one of the most common neurologic disorders that is characterized by recurrent seizures, and depending on the type of seizure, it could lead to a severe outcome. Epilepsy’s mechanism of development is not fully understood yet, but some of the
Linda Ines Zoungrana   +4 more
doaj   +1 more source

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]

open access: yes, 2017
The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria   +5 more
core   +1 more source

Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects : a cross-sectional study [PDF]

open access: yes, 2007
BACKGROUND : Animal data and postmortem studies suggest a role of oxidative stress in the Huntington's disease (HD), but in vivo human studies have been scarce.
Babić, Tomislav   +5 more
core   +1 more source

DISTURBANCES IN PROTEIN C SYSTEM IN PATIENTS SUFFERING FROM PERIODONTITIS [PDF]

open access: yesСаратовский научно-медицинский журнал, 2008
The present research is focused on defining the role of protein С system in the process of blood coagulation and fibrinolysis in patients suffering from different forms ofperiodontitis.
T.V. Simonyan, V.F. Kirichuk
doaj  

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