Results 41 to 50 of about 1,236,436 (312)

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs [PDF]

, 2019
We endeavored to identify objective blood biomarkers for pain, a subjective sensation with a biological basis, using a stepwise discovery, prioritization, validation, and testing in independent cohorts design. We studied psychiatric patients, a high risk
Jones, T., Judd, S., Khan, F., Kurian, S. M., Le-Niculescu, H., Levey, D. F., McCormick, M.A., Niculescu, A. B., Rogers, J., Roseberry, K., Soe, K. C., Wessel, A. R., White, F. A., Williams, A.   +13 more
core   +2 more sources

Neurological, psychological, and cognitive disorders in patients with chronic kidney disease on conservative and replacement therapy [PDF]

, 2016
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients.
Aceto, Paola, Carta, Maria, Davi, Leonardo, Frassetti, Nicla, Galani, Alessandro, Lai, Carlo, Lai, Silvia, Mariotti, Amalia, Mecarelli, Oriano, Mitterhofer, Anna Paola, Poli, Luca, Pulitano, Patrizia, Romanello, Roberto, Tasso, Giorgia, Testorio, Massimo, Zarabla, Alessia   +15 more
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

The Molecular Pathology of Prion Diseases [PDF]

, 2004
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen, Kretzschmar, Hans A., Vassallo, Neville   +2 more
core  

Natural history and outcome in systemic AA amyloidosis [PDF]

, 2007
BACKGROUND:Deposition of amyloid fibrils derived from circulating acute-phase reactant serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of many chronic inflammatory disorders.
Gallimore, JR, Gilbertson, JA, Gillmore, JD, Goodman, HJB, Hawkins, PN, Lachmann, HJ, Sabin, CA   +6 more
core   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Differences in leukocyte profile, gene expression, and metabolite status of dairy cows with or without sole ulcers [PDF]

, 2014
peer-reviewedSole ulcers are one of the most severe pathologies causing lameness in dairy cows and are associated with abnormal behavior and impaired production performance.
Aggarwal, Almeida, Almeida, Alsemgeest, Apple, Arya, Bernadette Earley, Bicalho, Bicalho, Buckham Sporer, Buckham-Sporer, Burton, Chao, Chen, Cooray, Davis, Derveaux, Fell, Fujishima, Galyean, Godson, Hart, Hellemans, Janeway, Jawor, Kansas, Keelin O’Driscoll, Knott, Kossaibati, Kulberg, Leeman, Lischer, Lischer, Matthew McCabe, McDowell, Moore, Murray, Nagata, Nocek, Opal, O’Driscoll, O’Driscoll, O’Driscoll, O’Loughlin, Preisler, Radostits, Rider, Shi, Smith, Tadich, Tarlton, Thoefner, Tomlinson, Watkins, Weber, Weber, Weissman, Whay, Whay, Wigmore   +59 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Health related effects of wheat varieties [PDF]

, 2020
Summarises the different effects wheat digestion has on human ...
Borgen, Anders
core  

Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis [PDF]

, 2019
The Ten-eleven translocation (TET) enzymes regulate gene expression by promoting DNA demethylation and partnering with chromatin modifiers. TET2, a member of this family, is frequently mutated in hematological disorders.
Abdel-Wahab, Agathocleous, Anders, Asmar, Chen, Cimmino, Cimmino, Delhommeau, Deplus, Dominguez, Fabiani, Garcia-Manero, Gardin, Giagounidis, Goasguen, Issa, Ito, Ito, Ito, Ito, Jiao, Kim, Ko, Komrokji, Kosmider, Lemonnier, Li, Love, Moran-Crusio, Mouly, Pan, Purton, Quivoron, Reddy, Sato, Schneider, Song, Tahiliani, Tefferi, Trapnell, Wang, Wang, Williams, Wu, Yu, Zhang   +45 more
core   +1 more source