Results 21 to 30 of about 833,559 (317)

Toxicological study of Zaleplon (Anxiolytic drug) in experimental animals

Zagazig Journal of Pharmaceutical Sciences, 2014
Anxiety disorders are among the most prevalent mental disorders in the general population. Nearly 30 million persons are affected in the United States, with women affected nearly twice as frequently as men.
Mostafa E. El-Naggar , Hassan M. El-Fayoumi , Nabila N. El-Maraghy , Wafaa I. El-Eraky , Siham M. El-Shenawy   +4 more
doaj   +1 more source

Activated protein C in epilepsy pathophysiology

Frontiers in Neuroscience, 2023
Epilepsy is one of the most common neurologic disorders that is characterized by recurrent seizures, and depending on the type of seizure, it could lead to a severe outcome. Epilepsy’s mechanism of development is not fully understood yet, but some of the
Linda Ines Zoungrana, Steven Didik, Hao Wang, Lily Slotabec, Ji Li   +4 more
doaj   +1 more source

A long-term "memory" of HIF induction in response to chronic mild decreased oxygen after oxygen normalization [PDF]

, 2007
Background Endothelial dysfunction (ED) is functionally characterized by decreased vasorelaxation, increased thrombosis, increased inflammation, and altered angiogenic potential, has been intimately associated with the progression and severity of ...
Green Dixy E, Ihnat Michael A, Green, Dixy E., Satyendra S Shenoy, Shenoy Satyendra S, Green DE, Thorpe JE, Ceriello Antonio, Kamat CD, Ceriello, Antonio, Antonio Ceriello, Shenoy, Satyendra S, Dixy E Green, Kamat Chandrashekhar D, Linda A Warnke, Warnke, Linda A., Warnke Linda A, Shenoy SS, Chandrashekhar D Kamat, Michael A Ihnat, Warnke LA, Kamat, Chandrashekhar D., Ihnat, Michael A., Ihnat M.A., Thorpe, Jessica E, Thorpe Jessica E, Jessica E Thorpe   +26 more
core   +1 more source

DISTURBANCES IN PROTEIN C SYSTEM IN PATIENTS SUFFERING FROM PERIODONTITIS [PDF]

Саратовский научно-медицинский журнал, 2008
The present research is focused on defining the role of protein С system in the process of blood coagulation and fibrinolysis in patients suffering from different forms ofperiodontitis.
T.V. Simonyan, V.F. Kirichuk
doaj  

RETRACTED: Tyrosine Kinase Inhibitors Target B Lymphocytes

Biomolecules, 2023
Autoimmune disorders and some types of blood cancer originate when B lymphocytes malfunction. In particular, when B cells produce antibodies recognizing the body’s proteins, it leads to various autoimmune disorders.
Nikki Lyn Esnardo Upfold, Pavlo Petakh, Aleksandr Kamyshnyi, Valentyn Oksenych   +3 more
doaj   +1 more source

Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers [PDF]

, 2013
Rationale New approaches to define factors underlying the immunopathogenesis of pulmonary diseases including sarcoidosis and tuberculosis are needed to develop new treatments and biomarkers. Comparing the blood transcriptional response of tuberculosis
Lipman, M, Derek Blankenship, Katalin A Wilkinson, Christine M Graham, Xu, Zhaohui, Vancheeswaran, Rama, Matthew P. R. Berry (130010), Anne O’Garra (130055), Dominique, Valeyre, Beynon, H, Banchereau, J, Rama Vancheeswaran, Guy Gorochov, Virginia Pascual, Anne O'Garra, Ling-pei Ho, Phillip Vanhems, Damien Chaussabel (26369), Pascual, V, Phillip Vanhems (441320), Xu, Z, Yvonne Kendrick (441315), Kendrick, Yvonne, Rozakeas, F, Chloe I. Bloom (130006), Lipman, Marc, Huw Beynon (441321), Vanhems, Phillip, Fotini Rozakeas, Wickremasinghe, Melissa, Christine M. Graham (130008), Miyara, M, Jacques Banchereau, Wickremasinghe, M, Marc Lipman, Matthew P. R. Berry, Diane Bouvry (441317), Yuanyuan Wang, Huw Beynon, Ferry, T, Berry, MP, Blankenship, D, Derek Blankenship (173502), Wilkinson, Robert J, Gilles Devouassoux (441316), Dominique, V, Ferry, Tristan, Paul S. Redford (441314), Robert J. Wilkinson, Berry, MPR, Matthew P R Berry, Melissa Wickremasinghe, Jacques Banchereau (4187), Wilkinson, Katalin A, Valeyre Dominique, Redford, Paul S, Zhaohui Xu, Saadatian, Mitra, Gilles Devouassoux, Berry, Matthew P R, Wang, Y, O\u27Garra, Anne, Yuanyuan Wang (20181), Rama Vancheeswaran (441322), Blankenship, Derek, Vancheeswaran, R, Katalin A. Wilkinson, Saadatian, M, Mitra Saadatian, Paul S. Redford, O'Garra, A, Chaussabel, Damien, Diane Bouvry, Devouassoux, G, Melissa Wickremasinghe (235318), Ho, LP, Robert J Wilkinson, Ho, Ling-Pei, Mitra Saadatian (441319), Guy Gorochov (89307), Wilkinson, KA, Pascual, Virginia, Rozakeas, Fotini, Katalin A. Wilkinson (130012), Robert J. Wilkinson (130050), Zhaohui Xu (130026), Damien Chaussabel, Gorochov, Guy, Graham, CM, Beynon, Huw, Valeyre, D, Tristan Ferry, Tristan Ferry (412308), Redford, PS, Bloom, Chloe I, Virginia Pascual (130037), Bouvry, D, Chaussabel, D, Chloe I. Bloom, Marc Lipman (130043), Vanhems, P, Bloom, CI, Paul S Redford, Chloe I Bloom, Ling-pei Ho (5655859), Wang, Yuanyuan, Yvonne Kendrick, Anne O’Garra, Dominique Valeyre, Gorochov, G, Kendrick, Y, Makoto Miyara, Bouvry, Diane, Banchereau, Jacques, Miyara, Makoto, Valeyre Dominique (441318), Christine M. Graham, Devouassoux, Gilles, Ho, L-P, Wilkinson, RJ, Makoto Miyara (199979), Graham, Christine M, Fotini Rozakeas (130019)   +122 more
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Recombinant factorVIII Fc fusion protein for the prevention and treatment of bleeding in children with severe hemophilia A [PDF]

, 2015
This work was supported by funding from Biogen, including funding for the editorial and writing support in the the development of this ...
Barnes, C, Nolan, B, Pasi, J, Neelakantan, S, Allen, G, Liesner, R, Gambino, G, Kulkarni, R, Cristiano, LM, Young, G, Pierce, GF, Mahlangu, J   +11 more
core   +1 more source

Genetic studies of familial myeloproliferative disorders [PDF]

, 2007
Hereditary thrombocythemia (HT) is an autosomal dominant disorder with clinical features resembling sporadic essential thrombocythemia. HT families share similar clinical symptoms caused by heterogeneous genetic alterations.
Liu, Kun
core   +1 more source

Diagnostic algorithm for comorbidity of babesiosis and dirofilariasis in dogs, taking into account the correlation of redox homeostasis and morphofunctional disorders of the hepatorenal and cardiopulmonary systems [PDF]

E3S Web of Conferences, 2021
Activation of lipid peroxidation due to a disorder of redox homeostasis in dogs with comorbidity of babesiosis and dirofilariasis causes the involvement of not only the components of the hepatorenal system, but also the cardiopulmonary system in the ...
Ushakova Tatyana, Derezina Tatyana, Kapelist Ivan, Fomina Anna   +3 more
doaj   +1 more source

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. [PDF]

, 2014
Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders ...
Susanne MA van der Pol, Male, David K, Cerutti, Camilla, Michael, G.J., Dongsheng Wu, van der Pol, SM, Sharrack, B, Romero, I.A., Baker, D., Michael, Gregory J, Simpson, Julie E., Cerutti, C., Simpson, J.E., Lopez-Ramirez, Miguel A., David Baker, Romero, IA, Wu, D.S., de Vries, H.E., Baker, David, King-Robson, J., Basil Sharrack, Simpson, Julie E, Michael, GJ, Wu, Dongsheng, van der Pol, Susanne M A, Hirst, Mark C, Julie E Simpson, Ignacio A Romero, Pryce, Gareth, Baker, D, Gregory J Michael, de Vries, Helga E, Romero, Ignacio A., Hirst, MC, King-Robson, Josh, de Vries, HE, Lopez-Ramirez, Alejandro, Mark C Hirst, David K Male, Male, DK, de Vries, Helga E., Gareth Pryce, Josh King-Robson, Camilla Cerutti, van der Pol, SMA, Romero, Ignacio A, van der Pol, S.M.A., Lopez-Ramirez, Miguel A, Male, D.K., Male, David K., Sharrack, B., King-Robson, J, van der Pol, Susanne M. A., Wu, D, Simpson, JE, Lopez-Ramirez, MA, Miguel A Lopez-Ramirez, Hirst, M.C., van der Pol, Susanne Ma, Cerutti, C, Helga E de Vries, Pryce, G, Pryce, G., Hirst, Mark C., Sharrack, Basil, Michael, Gregory J., Lopez-Ramirez, M.A.   +66 more
core   +1 more source