Results 251 to 260 of about 1,056,334 (396)

A Rare Type of Myeloma: A Case of Monoclonal IgD-Lambda. [PDF]

open access: yesCureus
Kaya R   +3 more
europepmc   +1 more source

Reversible High‐Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation

open access: yesAdvanced Science, EarlyView.
A calcium‐dependent, specific biorecognition between coagulation factor Xa (FXa) and zeolite is discovered. It alters the prothrombin activation pathway to a more efficient mechanism by mimicking the FXa/factor Va (FXa/FVa) interaction formed during the natural coagulation cascade.
Chaojie Shi   +9 more
wiley   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

open access: yesAdvanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen   +9 more
wiley   +1 more source

Proteome-Based Maternal Plasma and Serum Biomarkers for Preeclampsia: A Systematic Review and Meta-Analysis. [PDF]

open access: yesLife (Basel)
Starodubtseva N   +6 more
europepmc   +1 more source

Magnetic‐Guided Delivery of Antisense Oligonucleotides for Targeted Transduction in Multiple Retinal Explant and Organoid Models

open access: yesAdvanced Science, EarlyView.
Magnetic field‐guided MNP@ATR‐ASO nanocomplexes facilitate the targeted delivery of ASOs to ganglion cells or photoreceptors within retinal explants, thereby enhancing the efficacy of ASOs in correcting pre‐mRNA splicing abnormalities. Furthermore, the nanocomplexes improve ASO penetration and delivery in human retinal and inner ear organoid models ...
Xiuhong Ye   +13 more
wiley   +1 more source

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

open access: yesAdvanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu   +9 more
wiley   +1 more source

Decursin‐Loaded Nanovesicles Target Macrophages Driven by the Pathological Process of Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen   +13 more
wiley   +1 more source

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