Results 261 to 270 of about 1,056,334 (396)

Interaction of Heavy Metals (Cadmium and Selenium) in an Experimental Study on Goldfish: Hematobiochemical Changes and Oxidative Stress. [PDF]

J Xenobiot
Hashtjin YA, Raeeszadeh M, Khanghah AP.
europepmc   +1 more source

Manipulation of Oxygen Tension in Damaged Regions via Hypoxia‐Induced IPN Hydrogel Microspheres for Intervertebral Disc Regeneration

Advanced Science, EarlyView.
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou, Zhendong Lv, Zehao Chen, Yiming Xu, Chao Lin, Li Liu, Hao Chen, Bing Niu, Wenguo Cui, Yuhui Zhang   +9 more
wiley   +1 more source

Lipid-Coated Ag@MnO₂ Core-Shell Nanoparticles for Co-Delivery of Survivin siRNA in Breast Tumor Therapy. [PDF]

Int J Nanomedicine
Zhang J, Zha M, Xiao S, Filipczak N, Yalamarty SSK, Wu X, Gong C, Li X.   +7 more
europepmc   +1 more source

Chimeric Nanozyme Bacterial Outer Membrane Vesicles Reprograming Tumor Microenvironment for Safe and Efficient Anticancer Therapy

Advanced Science, EarlyView.
This study reports an innovative strategy to improve the safety of OMVs by shielding them with a sophisticated shell composed of DaFe shell and Au nanoparticles, which not only reduces the toxicity of OMVs during circulation but also enables rapid release of these therapeutically active components in tumor for combined therapy involving glucose ...
Fan Zhang, Qianqian Li, Haibing Dai, Weiqun Li, Xiang Chen, Huibin Wu, Shanming Lu, Ran Luo, Feng Li, Guihong Lu, Jianbo Yu, Lin Mei   +11 more
wiley   +1 more source

Comparative genomic analysis of Streptococcus suis sequence type 105 and development of a PCR diagnostic tool. [PDF]

PLoS One
Boueroy P, Chopjitt P, Borthong J, Wongsurawat T, Jenjaroenpun P, Duangjanchot R, Saiboonjan B, Hatrongjit R, Kerdsin A.   +8 more
europepmc   +1 more source

Bioengineered Tumor‐Derived Extracellular Vehicles Suppressed Colorectal Cancer Liver Metastasis and Bevacizumab Resistance

Advanced Science, EarlyView.
The upregulated CCL24 in CRC liver metastasis promotes the formation of inflammatory tumor‐associated fibroblast subsets and induces resistance to bevacizumab therapy. Downregulation of CCL24 significantly increased sensitivity to antiangiogenic therapy in CRC mouse model. Hence, a novel therapeutic target is identified for patients with CRC with liver
Junjiang Wang, Chunsheng Liu, Ping Wang, Zhiyuan Liu, Weixian Hu, Zejian Lv, Chengzhi Huang, Xueqing Yao   +7 more
wiley   +1 more source

Vascular-variant cardiac amyloid: Cardiac MRI and histopathological appearances. [PDF]

Acta Radiol Open
Flynn S, Fadalla K, Fabre A, Dodd JD.
europepmc   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source

Utilization of Native CRISPR-Cas9 System for Expression of Glucagon-like Peptide-1 in <i>Lacticaseibacillus paracasei</i>. [PDF]

Foods
Zheng M, Zhang S, Wang Y, Xie N, Wang X, Lv J, Pang X, Li X.   +7 more
europepmc   +1 more source