Results 21 to 30 of about 320,459 (212)

Machine learning evaluation for identification of M-proteins in human serum.

PLoS ONE
Serum electrophoresis (SPEP) is a method used to analyze the distribution of the most important proteins in the blood. The major clinical question is the presence of monoclonal fraction(s) of antibodies (M-protein/paraprotein), which is essential for the
Alexandros Sopasakis, Maria Nilsson, Mattias Askenmo, Fredrik Nyholm, Lillemor Mattsson Hultén, Victoria Rotter Sopasakis   +5 more
doaj   +1 more source

Search for breast cancer proteomic markers in total blood exosomes

Сибирский онкологический журнал, 2020
To improve early detection of cancer, search for tumor markers in biological fluids is of great importance. A significant portion of exosomes is associated with the surface of blood cells, however, the protein spectrum of such exosomes has not been ...
O. S. Tutanov, Y. S. Bakakina, K. V. Proskura, A. Б. Grigoryeva, V. E. Syakhovich, S. A. Beliaev, E. I. Ryabchikova, Y. P. Tsentalovich, P. P. Laktionov, S. N. Tamkovich   +9 more
doaj   +1 more source

ELECTROPHORETIC PATTERN OF BLOOD SERUM PROTEINS IN SINGLE HUMPED CAMELS "CAMELUS DROMEDARIUS" [PDF]

Assiut Veterinary Medical Journal, 1989
Forty dromedary camels of both sexes (25 male and 15 female) were included in this study. All camels were healthy and selected after careful clinical examination.
ALI EL-SEBAIE
doaj   +1 more source

Uji Aktivitas Lektin Biji Kebiul terhadap Kecepatan Penggumpalan Sel Darah Merah Manusia dalam Kondisi Patologis dan Implementasinya sebagai Modul Pembelajaran Kimia

Pendipa, 2018
[Lectin activities of kebiul seeds to the red blood cell agglutination speed in pathological condition and its implementation as a chemical learning module].
Yeni Trianah
doaj   +1 more source

Analysis of ovine transferrin polymorphisms and their relationship with blood metabolite variation in Makoei sheep breed [PDF]

مجله بیوتکنولوژی کشاورزی, 2010
In order to determine polymorphism of ovine transferrin and its association with blood metabolite in Makoei sheep, blood samples were collected from 576 male and female lambs using two types of Venoject (with or without EDTA).
Hossein Moradi, Amir hossein kHellatabadi farahani, Mohammad Moradi shahrbabak, Hossein Mohammadi   +3 more
doaj   +1 more source

High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia

Journal of Translational Medicine, 2009
Background When comparing myelogenous blasts from bone marrow and peripheral blood, immunophenotyping usually show a strong correlation of expression of surface antigens.
Thiel Eckhard, Sinha Pranav, Poland Julia, Nowak Daniel, Letsch Anne, Hütter Gero, Hofmann Wolf-K   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Evaluation of the Coagulant Effect of Zanjani and Latifi Viper Snake Venom Endemic in Iran

Trends in Peptide and Protein Sciences, 2016
The venom of the viper is very important in pharmaceutical usage, such as in the process of coagulation during medical care. This study aims to evaluate the coagulant factor of Latifi and Zanjani viper venom.
Milad Taherian, Hajar Yaghoobi, Mojgan Bandehpour   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source