Results 31 to 40 of about 329,241 (267)

Search for breast cancer proteomic markers in total blood exosomes

Сибирский онкологический журнал, 2020
To improve early detection of cancer, search for tumor markers in biological fluids is of great importance. A significant portion of exosomes is associated with the surface of blood cells, however, the protein spectrum of such exosomes has not been ...
O. S. Tutanov, Y. S. Bakakina, K. V. Proskura, A. Б. Grigoryeva, V. E. Syakhovich, S. A. Beliaev, E. I. Ryabchikova, Y. P. Tsentalovich, P. P. Laktionov, S. N. Tamkovich   +9 more
doaj   +1 more source

ELECTROPHORETIC PATTERN OF BLOOD SERUM PROTEINS IN SINGLE HUMPED CAMELS "CAMELUS DROMEDARIUS" [PDF]

Assiut Veterinary Medical Journal, 1989
Forty dromedary camels of both sexes (25 male and 15 female) were included in this study. All camels were healthy and selected after careful clinical examination.
ALI EL-SEBAIE
doaj   +1 more source

Uji Aktivitas Lektin Biji Kebiul terhadap Kecepatan Penggumpalan Sel Darah Merah Manusia dalam Kondisi Patologis dan Implementasinya sebagai Modul Pembelajaran Kimia

Pendipa, 2018
[Lectin activities of kebiul seeds to the red blood cell agglutination speed in pathological condition and its implementation as a chemical learning module].
Yeni Trianah
doaj   +1 more source

Analysis of ovine transferrin polymorphisms and their relationship with blood metabolite variation in Makoei sheep breed [PDF]

مجله بیوتکنولوژی کشاورزی, 2010
In order to determine polymorphism of ovine transferrin and its association with blood metabolite in Makoei sheep, blood samples were collected from 576 male and female lambs using two types of Venoject (with or without EDTA).
Hossein Moradi, Amir hossein kHellatabadi farahani, Mohammad Moradi shahrbabak, Hossein Mohammadi   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia

Journal of Translational Medicine, 2009
Background When comparing myelogenous blasts from bone marrow and peripheral blood, immunophenotyping usually show a strong correlation of expression of surface antigens.
Thiel Eckhard, Sinha Pranav, Poland Julia, Nowak Daniel, Letsch Anne, Hütter Gero, Hofmann Wolf-K   +6 more
doaj   +1 more source

Serum Protein Gel Agarose Electrophoresis in Captive Tigers

Animals, 2020
Given the endangered status of tigers (Panthera tigris), the health of each individual is important and any data on blood chemistry values can provide valuable information alongside the assessment of physical condition.
Daniela Proverbio, Roberta Perego, Luciana Baggiani, Giuliano Ravasio, Daniela Giambellini, Eva Spada   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source