Results 191 to 200 of about 2,909,536 (305)
Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger +5 more
wiley +1 more source
Stop the Clot, Spread the Word: Cancer and Blood Clots
If you have cancer and are undergoing cancer treatment, you can protect your health by learning about your risk for life-threatening blood clots.Stop the Clot, Spread the Word\uae is a public education campaign made possible by funding provided to the ...
core
Tandem extracorporeal blood purification therapies for sepsis and acute kidney injury in critically ill children: a state-of-the-art review. [PDF]
Shirode P +11 more
europepmc +1 more source
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar +11 more
wiley +1 more source
Successful treatment of severe cerebral malaria with artificial liver blood purification technology: A case report. [PDF]
Fan C +8 more
europepmc +1 more source
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Impact of different extracorporeal blood purification strategies during continuous renal replacement therapy in septic shock patients. [PDF]
Kovacevic P +8 more
europepmc +1 more source
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran +15 more
wiley +1 more source

