Results 51 to 60 of about 615,506 (245)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Activation of human NK cells by Plasmodium-infected red blood cells.

, 2012
This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Horowitz, Amir, Riley, Eleanor M
core   +1 more source

M-DC8+leukocytes - A novel human dendritic cell population [PDF]

, 1999
Dendritic cells (DC) constitute a heterogeneous leukocyte population having in common a unique capacity to induce primary T cell responses and are therefore most attractive candidates for immunomodulatory strategies.
Federle, Christine, Mayer, Elfriede, Poppe, Claudia, Rieber, Ernst Peter, Riethmüller, Gert, Schäkel, Knut   +5 more
core   +2 more sources

Latent profiles of falls self-awareness and associated factors in older maintenance hemodialysis patients

Scientific Reports
Falls are a significant concern for elderly Maintenance Hemodialysis (MHD) patients, with a rising fall-related mortality rate observed over the past decade.
Jun Xu, Suping Guo, Xintao Yu, Xiaojing Ji   +3 more
doaj   +1 more source

Thrombotic microangiopathy with transiently positive direct Coombs test in an adult with poststreptococcal acute glomerulonephritis: a case report

BMC Nephrology, 2022
Background To date, a few case reports have described the association between poststreptococcal acute glomerulonephritis (PSAGN) and hemolytic anemia/thrombocytopenia, both with or without a pathology similar to that of thrombotic microangiopathy (TMA ...
Dan Inoue, Takashi Oda, Sachiko Iwama, Takahiko Hoshino, Mitsuya Mukae, Takashi Sakai, Aki Kojima, Takahiro Uchida, Tadasu Kojima, Kentaro Sugisaki, Tomohiro Tomiyasu, Noriko Yoshikawa, Muneharu Yamada   +12 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Purification and properties of a plant Agglutinin [PDF]

, 1958
Thesis (M.A.)--Boston UniversityThis study involved work with extracts of the seeds of Bauhinia purpurea alba, in which an N specific lectin was found by Mäkelä (37) and Boyd and McMaster (16). There were two main purposes in mind.
Everhart, Donald Lee
core   +1 more source

Detection of Plasmodium falciparum male and female gametocytes and determination of parasite sex ratio in human endemic populations by novel, cheap and robust RTqPCR assays [PDF]

, 2017
The presence of Plasmodium falciparum gametocytes in peripheral blood is essential for human to mosquito parasite transmission. The detection of submicroscopic infections with gametocytes and the estimation of the gametocyte sex ratio are crucial to ...
Alano, Pietro, Avellino, Pamela, Lombardo, Fabrizio, Mangano, Valentina Dianora, Modiano, David, Ouédraogo, Jean Bosco, Santolamazza, Federica, Siciliano, Giulia, Yao, Franck Adama   +8 more
core   +2 more sources

HBP21 Alleviates Sepsis-Induced Acute Kidney Injury by Targeting PI3K/AKT-Mediated M1 Macrophage Polarization

Mediators of Inflammation
Conclusion: These findings suggest that HBP21 mitigates S-AKI pathogenesis via PI3K/AKT-mediated M2 macrophage polarization, underscoring its translational potential in renal injury therapy.
Na An, Mingzhi Xu, Ruman Chen, Cuijuan Wang, Yafei Bai   +4 more
doaj   +1 more source

Association between the serum uric acid-to-creatinine ratio and cardiovascular mortality in maintenance hemodialysis patients

Renal Failure
Background Uric acid is a risk factor for death in hemodialysis patients, but its exact role is still unclear. The serum uric acid-to-serum creatinine (SUA/SCr) ratio is a new indicator. This study aimed to clarify the relationship between this indicator
Wanqing Huang, Ning Ding, Yanping Zhang, Dongxia Qiu, Lin Wei, Chen Zhao, Zhuo Ren, Qian Wang, Kaiming Ren, Jiuxu Bai, Ning Cao   +10 more
doaj   +1 more source