Results 71 to 80 of about 2,909,536 (305)

A guideline for transfusion of red blood cells in surgical patients

open access: yes, 2000
Blood transfusion carries a real but unquantifiable risk of adverse outcome in surgical patients from infectious, immunological and cardiorespiratory morbid events.
National Blood Users Group
core  

Gel point and fractal microstructure of incipient blood clots are significant new markers of hemostasis for healthy and anticoagulated blood

open access: yes, 2010
Here we report the first application of a fractal analysis of the viscoelastic properties of incipient blood clots. We sought to ascertain whether the incipient clot's fractal dimension, Df, could be used as a functional biomarker of hemostasis.
Karl Hawkins   +10 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

SERUM LEVELS OF CEFSULODIN AND CEFOTIAM DURING BLOOD PURIFICATION IN UREMIC PATIENTS [PDF]

open access: yes, 1982
The serum levels of Cefsulodin and Cefotiam, new semisynthetic cepharosporines, in uremic patients were determined during blood purification. Cefsulodin was given in a single intravenous dose of 0.5g to uremic patients before blood purification.
逸見, 昭二   +5 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Developing Dietary Self-Management Personas for mHealth Tools Among Patients with Kidney Failure Undergoing Hemodialysis: A Multi-Method Study

open access: yesPatient Preference and Adherence
Zhishan Wu, Yuefeng Ding, Beiqian Tong, Sijie Gao, Jiayi HuangDepartment of Blood Purification, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ChinaCorrespondence: Jiayi Huang, Email gongzuo610@126 ...
Wu Z, Ding Y, Tong B, Gao S, Huang J
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Rationale for extracorporeal blood purification therapies in sepsis

open access: yes, 2000
Rationale for extracorporeal blood purification therapies in ...
C Ronco (13319244)   +2 more
core  

The Neutrophil Percentage-to-Albumin Ratio as a New Predictor of All-Cause Mortality in Maintenance Hemodialysis Patients

open access: yesInternational Journal of General Medicine
Changjing Shi,1,* Juan Wang,2,* Weichen Liu,2 Yiyi Mo,2 Yuan Huang,2 Xiaoxiao Wei,2 Dongmei Huo,2,* Aifang Huang2,* 1Information Technology Center, The First Affiliated Hospital of Guangxi Medical University, Nanning ...
Shi C   +7 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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