Transfusion-associated adverse events and implementation of blood safety measures - findings from the 2017 National Blood Collection and Utilization Survey. [PDF]
Serious transfusion‐associated adverse events are rare in the United States. To enhance blood safety, various measures have been developed. With use of data from the 2017 National Blood Collection and Utilization Survey (NBCUS), we describe the rate of ...
Savinkina AA +6 more
europepmc +2 more sources
HIV antiretroviral therapy and prevention use in US blood donors: a new blood safety concern.
CONTEXT Antiretroviral therapy (ART) to treat and pre-exposure prophylaxis (PrEP) to prevent HIV infection are effective tools to help end the HIV epidemic. However, their use could affect HIV transfusion-transmission risk.
Custer B +19 more
europepmc +2 more sources
West Nile and Usutu Virus Infections and Challenges to Blood Safety in the European Union. [PDF]
West Nile virus (WNV) and Usutu virus (USUV) circulate in several European Union (EU) countries. The risk of transfusion-transmitted West Nile virus (TT-WNV) has been recognized, and preventive blood safety measures have been implemented.
Domanović D +16 more
europepmc +2 more sources
Objective To analyze the specificity and Eplets of HLA allele-specific antibody in patients with platelet transfusion refractoriness (PTR). Methods HLA-A and B genotypes were detected by PCR-SBT, and HLA-Ⅰ antibodies in patients′ serum were detected by ...
Bing ZHANG +6 more
doaj +1 more source
A case of McLeod syndrome caused by a nonsense variation c.942G>A in the XK gene: A case report
McLeod syndrome is a rare XK gene-related progressive, debilitating disease involving multiple systems. The blood group phenotypes in McLeod syndrome patients usually display the Kx antigen loss and a decrease in the Kell blood group system antigen ...
Yanling Ying +12 more
doaj +1 more source
The Significance of RHD Genotyping and Characteristic Analysis in Chinese RhD Variant Individuals
BackgroundRhD is the most important and complex blood group system because of its highly polymorphic and immunogenic nature. RhD variants can induce immune response by allogeneic transfusion, organ transplantation, and fetal immunity.
Yanling Ying +11 more
doaj +1 more source
At present, many infectious pathogens, especially emerging/re-emerging pathogens, exist in the blood of voluntary blood donors and may be transmitted through blood transfusions.
Zhao Mengyi +20 more
doaj +1 more source
In order to treat the alloimmunization platelet transfusion refractoriness (PTR), human leukocyte antigen (HLA)-type and/or human platelet antigen (HPA)-type matched platelets between donors and patients are usually used.
Jielin Wang +13 more
doaj +1 more source
Health technology assessment of pathogen reduction technologies applied to plasma for clinical use [PDF]
Although existing clinical evidence shows that the transfusion of blood components is becoming increasingly safe, the risk of transmission of known and unknown pathogens, new pathogens or re-emerging pathogens still persists.
Berrino, Alexandra +18 more
core +1 more source
One Health approach for West Nile virus surveillance in the European Union: relevance of equine data for blood safety. [PDF]
West Nile virus (WNV) infection is notifiable in humans and equids in the European Union (EU). An area where a human case is detected is considered affected until the end of the mosquito transmission season (week 48) and blood safety measures have to be ...
Young JJ +5 more
europepmc +2 more sources

