Results 71 to 80 of about 5,621,310 (257)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Blood Transfusion Service Board annual report 1999
, 2000 I was appointed to chair the Board of the BTSB in April 1999 and have been engaged on a very deep learning curve since then. The organisation is in the throes of enormous changes under the very able direction of the CEO and the National Medical Director.
Blood Transfusion Service Board (BTSB)
core
Standards for blood donors selection are established to ensure the safety of both donors and recipients, as well as the quality of blood products and an adequate blood supply.
Expert Panel on Blood Pressure Screening Strategies for Blood Donor Selection
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Prevention of Transfusion-Transmitted Infections: Dilemmas
Frontiers in Medicine, 2017 To make blood components and blood products safe, many safety measures are applied to avoid transfusion-transmitted infections. Defining a balanced safety policy is not easy, we face several dilemmas: How safe should blood be?
Hans L. Zaaijer
doaj +1 more source
Lowering blood alcohol content levels to save lives: A European case study [PDF]
Road safety has become an increasing concern in developed countries due to the significant amount of fatalities and the associated economic losses. Only in 2005 these losses rose to 200,000 million euros, a considerable sum approximately 2% of GDP that ...
Daniel Albalate
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Lowering blood alcohol content levels to save lives, the european experience [PDF]
Road safety has become an increasing concern in developed countries due to the significant amount of mortal victims and the economic losses derived. Only in 2005 these losses rose to 200.000 million euros, a significant amount – approximately the 2% of ...
Daniel Albalate
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A study on confidential unit exclusion at Shiraz Blood Transfusion Center, Iran
Asian Journal of Transfusion Science, 2016 Background: Confidential unit exclusion (CUE) system has been designed to enhance transfusion safety as an extra additive approach. Aims: This study was designed to survey demographic characteristics, prevalence of serologic markers, and reasons of ...
Leila Kasraian, Mohammad Hossein Karimi
doaj +1 more source