Results 61 to 70 of about 5,621,310 (257)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Changing the standard of blood management in Australia: An overview

open access: yesJournal of Perioperative Nursing, 2018
In 2012 the Patient Blood Management (PBM) guidelines were published by the National Blood Authority, providing a standard of practice for clinicians across Australia.
Alana Delaforce, Jed Duff, Nick Ralph
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Other title: Highway safety plan

open access: yes, 2010
FFY 2010-; Vol. for FFY 2012- issued by: Office of Criminal Justice Services, Ohio Dept.

core   +3 more sources

Issued by the National Blood Users Group

open access: yes, 2002
Rapid and continuing loss of blood is life-threatening. Ensuring that tissue oxygenation is maintained at a level consistent with avoidance of critical ischaemic organ damage and irreversible organ failure demands speed and skill.
National Blood Users Group
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A guideline for transfusion of red blood cells in surgical patients

open access: yes, 2000
Blood transfusion carries a real but unquantifiable risk of adverse outcome in surgical patients from infectious, immunological and cardiorespiratory morbid events.
National Blood Users Group
core  

Expert consensus on unmanned aerial vehicle blood transportation in Shenzhen

open access: yes
The unmanned aerial vehicle (UAV) blood transportation service is a convenient blood delivery way provided by the Shenzhen Blood Centre. It is also an essential part of the “Air-ground Integrated” blood delivery model. UAV blood delivery can avoid ground
Blood Transfusion Branch of Shenzhen Medical Association Expert Consensus Writing Group on Unmanned Aerial Vehicle Blood Transportation in Shenzhen
core   +1 more source

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