Results 61 to 70 of about 1,015,983 (312)
Community Attitudes to Road Safety, 1995
, 2019 The survey is the eighth in a series of national studies conducted since October 1986 for the Federal Office of Road Safety, designed to monitor key community attitudes toward road safety issues.Adams, Kathryn, Hejtamek, Sandra, Mitchell-Taverner, Philip +2 morecore +1 more sourceEstimated Risk of HIV Acquisition and Practice for Preventing Occupational Exposure: A Study of Healthcare Workers at Tumbi and Dodoma Hospitals, Tanzania. [PDF]
, 2013 Health care workers (HCWs) are at risk of acquiring human immuno-deficiency virus (HIV) and other infections via exposure to infectious patients' blood and body fluids.Hamisi M Malebo, Mashoto, Kijakazi O, Malebo, Hamisi M, Makundi, Emmanuel, Mubyazi, Godfrey M, Mohamed, Hussein, Malebo, H. M, Mohamed, H, Kijakazi O Mashoto, Emmanuel Makundi, Mashoto, K. O., Mubyazi, G. M, Hussein Mohamed, Makundi, E, Godfrey M Mubyazi +14 morecore +1 more sourceAddition of Sodium Pyruvate to Stored Red Blood Cells Attenuates Liver Injury in a Murine Transfusion Model
Mediators of Inflammation, 2016 RBCs undergo numerous changes during storage and stored RBCs may induce adverse effects, ultimately resulting in organ injury in transfusion recipients.Sha Xia, Gan Chen, Bo Wang, Yujing Yin, Zhenwei Sun, Jingxiang Zhao, Penglong Li, Lian Zhao, Hong Zhou +8 moredoaj +1 more sourceA systematic genotype and subgenotype re-ranking of hepatitis B virus under a novel classification standard
Heliyon, 2019 Background and aim: It is commonly noticed that chaotic and inefficient subgenotyping are universally used academically and clinically, a standardized HBV genotype/subgenotype classification criterion is urgently acquired.Yonghua Yin, Kai He, Bingting Wu, Min Xu, Lianming Du, Wei Liu, Pu Liao, Yu Liu, Miao He +8 moredoaj +1 more sourceLongitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay +15 morewiley +1 more sourceSurveillance of HIV-1 genetic subtypes and diversity in the US blood supply
, 2000 BACKGROUND: Recent reports of variant (non-subtype B) HIV infections in US populations have raised concerns about the sensitivity of subtype B virus-based donor screening and diagnostic assays.Finlayson, T., Gwinn, M., Busch, M. P., Sullivan, M. T., Oliveira, C. F. de, Machado, D. M., Kessler, D., Lackritz, E. M., Operskalski, E. A., Williams, A. E., Mosley, J. W., Diaz, R. S. +11 morecore +1 more sourceLong term (5 Year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial [PDF]
, 2011 <b>Background:</b>
Bronchial thermoplasty (BT) is a bronchoscopic procedure that improves asthma control by reducing excess airway smooth muscle.Rubin AS, Rubin Adalberto S, Rubin, A.S., Paul A Corris, D. McCormack (7660568), Adalberto S Rubin, Siersted, HC, Gerard Cox, G. Cox (7598651), Shargill, N.S., Narinder S Shargill, Niven, Robert M, Ronald Olivenstein, Laviolette, M., Robert M Niven, Siersted, H.C., Corris, PA, Rubin, Adalberto S., Corris Paul A, Olivenstein R, Olivenstein Ronald, Olivenstein, R, Shargill, NS, McCormick, D., Rubin, AS, Neil C Thomson, Shargill Narinder S, null null, Laviolette M, Laviolette, M, Rubin, Adalberto S, Olivenstein, R., the AIR Trial Study Group (7660574), AIR Trial Study Group, N.C. Thomson (7660550), Pavord, I.D., Shargill NS, Corris, Paul A., Pavord Ian D, Pavord, Ian D., Niven, RM, Shargill, Narinder S., Michel Laviolette, Thomson, Neil C., David McCormack, N.S. Shargill (7660571), R.M. Niven (7660556), Corris, Paul A, P.A. Corris (7660559), Corris PA, Pavord ID, Corris, P.A., Laviolette Michel, Cox, G, Niven RM, Cox, Gerard, Niven, Robert M., H.C. Siersted (7660562), McCormack David, Pavord, ID, Siersted Hans, Ian D Pavord, McCormack, D, McCormack D, Thomson, N.C., Siersted, Hans Christian, Ian D. Pavord (7582361), Siersted, Hans C., A.S. Rubin (7660553), McCormack, David, Olivenstein, Ronald, Thomson Neil C, R. Olivenstein (7660565), Thomson, NC, Laviolette, Michel, Thomson, Neil C, Niven, R.M., Hans Christian Siersted, Thomson NC, Niven Robert M, Shargill, Narinder S, Cox Gerard, Cox G, Pavord, Ian D, M. Laviolette (3501599), Cox, G., Siersted HC +86 morecore +1 more sourceA novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz +9 morewiley +1 more sourceEstablishing a screening strategy for non-discriminatory reactive blood donors by constructing a predictive model of hepatitis B virus infection status from a single blood center in China
Frontiers in Public HealthBackgroundWhen employing the transcription-mediated amplification method for screening blood donors, there are some non-discriminatory reactive results which are screening assay reactive but HBV-DNA discriminatory assay negative.Danxiao Wu, Danxiao Wu, Yiqin Hu, Min Wang, Yaling Wu, Yaling Wu, Jie Dong, Jie Dong, Jinhui Liu, Jinhui Liu, Wei Hu, Wei Hu +11 moredoaj +1 more sourceDerivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang +7 morewiley +1 more source