Results 71 to 80 of about 181,790 (260)

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Development of a 3D Vascular Network Visualization Platform for One-Dimensional Hemodynamic Simulation

Bioengineering
Recent advancements in computational performance and medical simulation technology have made significant strides, particularly in predictive diagnosis.
Yan Chen, Masaharu Kobayashi, Changyoung Yuhn, Marie Oshima   +3 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

In vitro experiment and computational fluid dynamics simulation study on blood pump for total cavopulmonary connection circulation

Frontiers in Bioengineering and Biotechnology
ObjectiveThis study aimed to address the compromised hemodynamics in patients with total cavopulmonary connection circulation after Fontan surgery. While the Fontan procedure effectively separates systemic and pulmonary venous blood, resolving organ ...
Yong Wu, Tong Chen, Yunhan Cai, Shengzhang Wang, Shengzhang Wang, Shengzhang Wang, Haiyan Lu   +6 more
doaj   +1 more source

Simulation research on excitation system of multi-electrode blood flow meter

Journal of Hebei University of Science and Technology, 2019
In order to monitor human blood flow rate and flow velocity distribution, a blood flow meter based on multi-electrode electromagnetic measurement has been proposed to measure the flow velocity of the arteriovenous blood by obtaining the induced voltage ...
Yuyang ZHAO, Dongyu WAN, Jian YAO, Xueli WU   +3 more
doaj   +1 more source

Micro-simulation of Blood Flow

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B, 2004
We have developed a microscopic blood model, that can express the deformation of an erythrocyte in micro-circulation, based on the Smoothed Particle Hydrodynamics (SPH) method. In the method, plasma fluid is discretized by SPH particles and an erythrocyte is modeled by internal SPH particles wrapped in elastic membrane particles.
TAKANO, Tatsuo, TANAKA, Nobuatsu, MASUZAWA, Toru   +2 more
openaire   +2 more sources

Sodium Alginate‐Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection

Advanced Healthcare Materials, EarlyView.
A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood, Venkata S. Akshintala, Surya T. Evani, Rebecca A. Krimins, Yihan Wang, Keith Freel, Ahmed Ibrahim, Saowanee Ngamruengphong, Mouen Khashab, Stephen W. Hoag   +9 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Wearable OLED‐Assisted Photodynamic Cancer Therapy Using Chlorin e6‐Loaded Pluronic Nanocapsules as Photosensitizers

Advanced Healthcare Materials, EarlyView.
A novel photodynamic therapeutic approach has been employed for anticancer therapy, utilizing chlorin e6‐loaded Pluronic nanocapsules and a wearable organic light‐emitting diode light source. This has shown significant in vivo antitumor efficacy with minimal off‐target toxicity. The innovative combination of a wearable light source and photosensitizers
Hyeryeon Oh, Seung Min Jeong, Cheol Hui Park, Panmo Son, Yeseo Lee, Heebeom Koo, Won Il Choi, Kyung Cheol Choi   +7 more
wiley   +1 more source