Results 121 to 130 of about 360,574 (311)

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

open access: yesAdvanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang   +7 more
wiley   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

open access: yesAdvanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa   +6 more
wiley   +1 more source

The Effect of a Care Bundle on the Rate of Blood Culture Contamination in a General Intensive Care Unit

open access: yesAntibiotics
Background/objectives: Blood culture (BC) contamination is a frequent problem which leads to increased laboratory workload, inappropriate use of antibiotics and the associated adverse events, and increased healthcare costs.
Fani Veini   +3 more
doaj   +1 more source

Experiment requirements: Vitamin D metabolites and bone demineralization, Spacelab 2, experiment no. 1 [PDF]

open access: yes
As a contribution toward an understanding of the molecular basis of bone loss, mineral imbalance, and increasing fecal calcium under conditions of prolonged space flight, the blood levels of biologically active vitamin D metabolites of flight crew ...
Holton, E. M.   +2 more
core   +1 more source

Bioinspired, Mitochondria‐Targeted Single‐Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

open access: yesAdvanced Materials, EarlyView.
A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang   +16 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Tough and Rapidly Relaxing Hydrogels Via Programmable Crosslink Kinetics

open access: yesAdvanced Materials, EarlyView.
A kinetic programming strategy encodes supramolecular crosslink lifetimes in single polymer networks via stoichiometric control of fast and slow hostguest interactions. This enables predictable stress relaxation on biologically relevant timescales (0.1‐100 s) while maintaining exceptional toughness (up to 14,500 J m−2), resolving the long‐standing ...
Yuanyuan Wei   +3 more
wiley   +1 more source

Impact of a large-scale educational intervention program on venous blood specimen collection practices. [PDF]

open access: yesBMC Health Serv Res, 2013
Bölenius K   +5 more
europepmc   +1 more source

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