More than a drop of blood: the paradigm shift of a large-volume capillary sample for point-of-care clinical diagnostics. [PDF]
Damhorst GL, Rao A, Pollock NR.
europepmc +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Observation on status quo of nurses’ blood specimen collection operation
CAO Qiujun, WU Yan
doaj
Closed loop full process management and application of body fluid specimens in hospitalised patients. [PDF]
Zhao D, Peng Y, Wang J.
europepmc +1 more source
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source
Clinician perspectives on blood culture practice and diagnostic stewardship in regional emergency departments. [PDF]
Thomas E +3 more
europepmc +1 more source
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian +7 more
wiley +1 more source
Ultrasound-guided skeletal muscle biopsy technique permits measurement of structural, functional, cellular and biochemical properties. [PDF]
Barber A +8 more
europepmc +1 more source
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma +10 more
wiley +1 more source
Antimicrobial susceptibility trends of WHO critical Gram-negative pathogens in Fijian Hospitals, 2016-2021. [PDF]
Baleivanualala SC +13 more
europepmc +1 more source

