Results 231 to 240 of about 551,858 (358)

Detection of Paraburkholderia in Clinical Specimens Associated with Use of Nonsterile Ultrasound Gel for Percutaneous Procedures - United States, Canada, and Israel, May 2023⎯April 2025. [PDF]

MMWR Morb Mortal Wkly Rep
Lim S, Vagnone PS, Marshall NC, Lees C, Dale JL, Smith B, Palavecino E, Lynfield R, Gross A, Knowles K, Michael-Gayego A, Temper V, Strahilevitz J, Oster Y, Grupel D, Reshef D, Motro Y, van der Walt PJ, Croxen MA, Smith SW, Lee B, Tipples GA, Warren B, Moran-Gilad J.   +23 more
europepmc   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

When Numbers Lie: A Case Report of Falsely Low Hemoglobin Due to Preanalytical Error Leading to Unnecessary Interventions. [PDF]

Cureus
Zoubi A.
europepmc   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Laboratory epidemiology of <i>Salmonella</i> infections and multi-drug resistance profiles in Nigeria: Barriers, challenges and proposed solutions. [PDF]

One Health
Banibella A, Saad N, Eyad J, Chambuso R.
europepmc   +1 more source

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, EarlyView.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source

Clostridium difficile colonization among patients with clinically significant diarrhea and no identifiable cause of diarrhea [PDF]

, 2018
Bongu, Jahnavi, Burnham, Carey-Ann D, Cass, Candice, Dubberke, Erik R, Henderson, Jeffrey P, Hink, Tiffany, Kwon, Jennie H, Reske, Kimberly A   +7 more
core   +1 more source

Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens.

JAMA Netw Open
Tavakoli NP, Sack V, Handel AS, Giacinto A, Pearce M, Ojukwu I, McManaman C, St-Pierre M, DiAntonio L, Saavedra-Matiz C, Brandon CJ, Steen L, Salvatore CM, Sood S, Piwoz JA, John M, DeLaMora P, Nolan SM, Ungar SP, Weiner LB, Daniels D, Nayak JL, Quinn M, Weinberg GA, Hicar MD, Rebello G, Taormina G, Daniel JM, Hymes S, Nachman S, Bradley S, Kay DM, Caggana M.   +32 more
europepmc   +1 more source