Results 71 to 80 of about 10,062,834 (296)

Study on the stability of antipsychotic drugs in clinical samples within serum collection tubes with and without separating gel

Frontiers in Psychiatry
BackgroundThe study evaluated loss due to adsorption of selected antipsychotic drugs in serum samples collected in blood collection tubes with and without separation gel using real clinical specimens.MethodsClinical serum specimens (n = 30 per drug) were
Wenjuan Dong, Xin Cheng, Zhi Chu, Haifeng Zhang, Jing He, Xue Zhang   +5 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Navigating preanalytical challenges: a real-world study on single-tube pneumatic tube systems

Frontiers in Physiology
PurposePneumatic tube systems (PTS) accelerate the transport of samples in the laboratory but may lead to preanalytical hemolysis. Samples may rest before transport during busy times, but the effect on test accuracy is unclear.
Lisha Li, Xiaofei Zhang, Nannan Xu, Miaoli Shao, Binxuan Chen, Feng Wu, Qi Zhao, Wensheng Wang, Jianxin Yan, Zhiheng Wang, Renfang Zhou   +10 more
doaj   +1 more source

Residual Negative Pressure in Vacuum Blood-Collection Tube and Hemolysis in Pediatric Blood Specimens

Laboratory Medicine, 2019
ABSTRACT Objective To determine a method to reduce specimen hemolysis rates in pediatric blood specimens. Methods A total of 290 blood specimens from pediatric patients were classified into the capped group or uncapped group.
Jing Hu, Qiao-Xin Zhang, Tong-Tong Xiao, Mei-Chen Pan, Ying-Mu Cai   +4 more
openaire   +2 more sources

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Breakfast can Affect Routine Hematology and Coagulation Laboratory Testing: An Evaluation on Behalf of COLABIOCLI WG-PRE-LATAM

TH Open, 2019
Laboratories worldwide perform both hematological and coagulation testing on patients avoiding fasting time. In 2017, the Latin America Confederation of Clinical Biochemistry (COLABIOCLI) commissioned the Latin American Working Group for Preanalytical ...
Maria Elena Arredondo, Eduardo Aranda, Rubén Astorga, Lorena Michele Brennan-Bourdon, Marise Danielle Campelo, Silvia Flores, Claudio Medel, Ignacio Manríquez, Patricia Ochoa, Beatriz Varela, Carlos Vega Salinas, Gabriel Lima-Oliveira   +11 more
doaj   +1 more source

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

Advanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum, Kai P. Barbian, Florian Neuhaus, Gerrit Sitarz, Carolin Nölke, Sebastian V. Jansen, John Linkhorst, Lukas T. Hirschwald, Sebastian Brosch, Christian Certa, Ulrich Steinseifer, Matthias Wessling, Jutta Arens, Arjang Ruhparwar, Bettina Wiegmann   +14 more
wiley   +1 more source

Effect of blood collection tube variability on biochemistry test reliability: focus on possible contamination and other discrepancies

Türk Biyokimya Dergisi
The aim of this study was to evaluate the effects of five different brands of gel separator biochemistry serum tubes (BD-Vacutainer, Greiner Bio One-Vacuette, Samplix, Pirmax and Ayset) on routine biochemistry test measurement results performed with both
Balci Tevfik, Ayan Durmuş, Zeybek Aydoğan Kader, Küçükkaya Onur, Demirtaş Ayşe, Özdemir Muammer, Bayram Ergül, Bayraktar Bariş   +7 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source