Results 81 to 90 of about 10,062,834 (296)

Collection Spotlight: Blood Money

open access: yes, 2019
Background: The 2019 'Collection Spotlight: Blood Money' exhibition was a major showcase of the Blood Money research project. It featured four of the printed works that are the critical part of the Exchange Terminal concept.
Presley, Ryan, Betts, Guy
core  

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

open access: yesAdvanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris   +11 more
wiley   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen   +20 more
wiley   +1 more source

An Assessment of Individual Preference for a Novel Capillary Blood Collection System [Corrigendum]

open access: yesPatient Preference and Adherence
Pourafshar S, Parikh M, Abdallah B, Al Thubian N, Jacobson JW. Patient Prefer Adherence. 2024;18:531–541. Page 532, Materials and Methods, Capillary Blood Collection section, lines 3 and 4, the text “and EDTA tubes (intended for hemoglobin ...
Pourafshar S   +4 more
doaj  

Impact of sampling technique, anticoagulant, processing delay, and temperature on murine platelet function in whole blood

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Platelets are highly sensitive to subtle changes in their microenvironment, making functional analyses challenging and prone to variation. Advances in understanding how experimental procedures influence human platelet activation have improved
Silvia Maria Grazia Trivigno   +2 more
doaj   +1 more source

Management of Blood Transfusion Services in India: An Illustrative Study of Maharashtra and Gujarat States [PDF]

open access: yes
Blood is a vital healthcare resource routinely used in a broad range of hospital procedures. It is also a potential vector for harmful, and sometimes fatal, infectious diseases such as HIV, HBV, and HCV.
Ramani, K. V.   +2 more
core  

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

open access: yesAdvanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng   +15 more
wiley   +1 more source

An Assessment of Individual Preference for a Novel Capillary Blood Collection System

open access: yesPatient Preference and Adherence
Shirin Pourafshar,1 Monisha Parikh,2 Bilal Abdallah,2 Nasrin Al Thubian,3 James W Jacobson4 1Medical Affairs, Becton, Dickinson and Company, Sparks, MD, USA; 2Medical Affairs, Becton, Dickinson and Company, Franklin Lakes, NJ, USA; 3Medical Affairs ...
Pourafshar S   +4 more
doaj  

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu   +13 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy