Results 91 to 100 of about 4,020,463 (296)

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Suppression of adaptive immunity to heterologous antigens during plasmodium infection through hemozoin-induced failure of dendritic cell function [PDF]

, 2006
Dendritic cells (DCs) are central to the initiation and regulation of the adaptive immune response during infection. Modulation of DC function may therefore allow evasion of the immune system by pathogens.
Di Lorenzo, Caterina, Phillips, R. Stephen, Millington, Owain R., Brewer, James M., Garside, Paul   +4 more
core   +2 more sources

A hepatitis C avidity test for determining recent and past infections in both plasma and dried blood spots [PDF]

, 2013
DBS testing has been used successfully to detect HCV antibody positive individuals. Determining how long someone has been infected is important for surveillance initiatives. Antibody avidity is a method that can be used to calculate recency of infection.
Goldberg, David J., Aitken, Celia, Carman, W.F., Gunson, R.N., Kean, J., Cameron, Sheila O., Carman, W., Goldberg, D.J., Hutchinson, Sharon, Cameron, S., Aitken, C., Shepherd, S.J., Hutchinson, Sharon; id_orcid, Keen, Joy, Shepherd, Samantha J., Hutchinson, S.J.   +15 more
core   +2 more sources

Issued by the National Blood Users Group

, 2002
Rapid and continuing loss of blood is life-threatening. Ensuring that tissue oxygenation is maintained at a level consistent with avoidance of critical ischaemic organ damage and irreversible organ failure demands speed and skill.
National Blood Users Group
core  

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

A guideline for transfusion of red blood cells in surgical patients

, 2000
Blood transfusion carries a real but unquantifiable risk of adverse outcome in surgical patients from infectious, immunological and cardiorespiratory morbid events.
National Blood Users Group
core  

Flow chart of blood stream infection (BSI) episodes, patients and corresponding serovars.

, 2012
Flow chart of blood stream infection (BSI) episodes, patients and corresponding serovars.
Erika R. Vlieghe (111167), Chun Kham (111183), Thong Phe (111169), Birgit De Smet (111172), Jan A. Jacobs (111212), Willy E. Peetermans (111205), Chhun H. Veng (111177), Lut Lynen (111200), Sophie Bertrand (111189), Raymond Vanhoof (111194)   +9 more
core   +1 more source

Anaemia in acute HIV-1 subtype C infection. [PDF]

, 2007
BACKGROUND: The high prevalence of anaemia and the increased morbidity and mortality associated with anaemia during AIDS has been well described yet there has been little information about anaemia and changes in haemoglobin levels during acute and early ...
Auld, Sara C, van Loggerenberg, Francois, Auld Sara C., Loggerenberg, Francois van, Sobieszczyk Magdalena E., Abdool Karim Salim S., Grobler Anneke, Grobler, Anneke, Anneke Grobler, Auld, Sara C., Itua Iriogbe, Mlisana, Koleka Patience., Iriogbe, Itua, Sobieszczyk, Magdalena E, van Loggerenberg, F, Mlisana, K, Iriogbe, Itua., Salim S Abdool Karim, Mlisana, Koleka, Auld, SC, Abdool Karim, Salim Safurdeen., Sobieszczyk, ME, Grobler, A, Magdalena E Sobieszczyk, Williamson, Carolyn., Carolyn Williamson, Francois van Loggerenberg, Abdool Karim, Salim S, Sobieszczyk, Magdalena E., Iriogbe, I, Williamson Carolyn, Abdool Karim, SS, Sara C Auld, Team, for the CAPRISA Acute Infection Study, Williamson, Carolyn, Williamson, C, Grobler, Anna Christina., van Loggerenberg, Francois., van Loggerenberg Francois, Karim, Salim S Abdool, Koleka Mlisana, Iriogbe Itua, Mlisana Koleka, CAPRISA Acute Infection Study Team   +43 more
core   +2 more sources

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Peripheral cytokine responses to Trichuris muris reflect those occurring locally at the site of infection [PDF]

, 2000
The study of human cellular immune responses to parasite infection under field conditions is very complex. Often, the only practical site from which to sample the cellular responses is the peripheral blood.
Betts, Catherine, Taylor, Matthew D, Taylor, Matthew D., Kathryn J. Else, Matthew D. Taylor, Betts, Catherine J., Else, Kathryn, Else, Kathryn J., Catherine J. Betts   +8 more
core   +1 more source