Results 121 to 130 of about 4,020,463 (296)
Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Abstract Patients with substance use disorder (SUD) represent a high‐complexity, high‐cost population on hospital medicine services, yet their admissions are systematically under‐reimbursed due to narrow clinical documentation. Increasingly, hospital‐based addiction consultation service (ACS) clinicians provide dedicated addiction care to medically ...
Philip A. Durney +2 more
wiley +1 more source
Characterising HIV-associated Mycobacterium tuberculosis blood stream infection [PDF]
Despite the success of antiretroviral therapy roll-out, one-million people still die with HIV-infection annually. In high-burden settings, tuberculosis remains the most common proximal cause of hospital admission and death in people living with HIV.
Barr, DA
core +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Saar Anis +3 more
wiley +1 more source
Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley +1 more source
The human P-k histo-blood group antigen provides protection against HIV-1 infection
Several human histo-blood groups are glycosphingolipids, including P/P1/P-k. Glycosphingolipids are implicated in HIV-host-cell-fusion and some bind to HIV-gp120 in vitro.
Ma, Xue-Zhong +14 more
core +1 more source
Exploring the Management Literature of Sustainable Healthcare: A Bibliometric and Content Analysis
ABSTRACT This study aims to provide a comprehensive overview of sustainable healthcare from the perspective of the management literature. Relevant publications were retrieved from the Scopus database. A total of 85 publications from 1997 to July 2024 were analyzed using the R bibliometrix package. Findings suggest this is a nascent area of study in the
Donna V. Jones +2 more
wiley +1 more source
Staphylococcal blood stream infections in cancer patients
Ahmed, NH, Baruah, FK, Grover, RK
openaire +3 more sources
Nosocomial blood stream infection in Auckland Healthcare hospitals
An open access copy of this article is available and complies with the copyright holder/publisher conditions.Aim. To report the epidemiology of nosocomial bloodstream infections in Auckland Healthcare Hospitals. Methods.
Morris, A.J. +2 more
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