Results 61 to 70 of about 4,020,463 (296)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Fungal Blood Stream Infection: The Emerging Nosocomial Mayhem in Intensive Care Unit

Journal of Pure and Applied Microbiology
Bloodstream infections (BSI) belong to the most detrimental healthcare associated infections (HAI) that have an impact on the treatment result of patients hospitalised to intensive care units.
Kamaljeet, Mohit Thalquotra, Pratiksha Dhamal, Narayana Kamath   +3 more
doaj   +1 more source

FREQUENCY OF STAPHYLOCOCCUS AUREUS IN BLOOD STREAM INFECTIONS AND THEIR DRUG SUSCEPTIBILITY PATTERN

Gomal Journal of Medical Sciences, 2019
Background: Staphylococcus aureus is important cause of blood stream infections. The objectives of this study were to determine the frequency of Staphylococcus aureus in blood stream infections and their antimicrobial drug susceptibility pattern ...
Nadia Aslam, Nazma Kiran, Naima Mehdi, Mateen Izhar, Tanveer Zia, Hadiqa Tul Hafsa   +5 more
doaj   +1 more source

The human immune response to tuberculosis and its treatment: a view from the blood. [PDF]

, 2015
The immune response upon infection with the pathogen Mycobacterium tuberculosis is poorly understood, hampering the discovery of new treatments and the improvements in diagnosis.
van Helden, Paul, van Helden, P., Cliff, Jacqueline M, Kaufmann, Stefan HE, O'Garra, Anne, Kaufmann, S., McShane, H., O'Garra, A., Cliff, J., McShane, Helen   +9 more
core   +1 more source

Battery‐Inspired Electrochemical Synapses for Neuromorphic Applications

Advanced Science, EarlyView.
Battery‐ion‐inspired synaptic devices integrate diverse electrolyte systems (solid, ion‐gel, liquid) with transition metal oxides, two‐dimensional materials, and organic channels to regulate ion‐electron coupling. By tailoring ion transport and host interactions, these platforms enable controllable plasticity and energy‐efficient implementations for ...
Won Woo Lee, SeongCheol Jang, Wangmyung Choi, Jaewon Park, Jaehyun Hur, Hocheon Yoo, Hyun‐Suk Kim   +6 more
wiley   +1 more source

Blood stream Infections in chronic hemodialysis patients - characteristics and outcomes

BMC Nephrology
Introduction Bloodstream Infections (BSI) are a major cause of death and hospitalization among hemodialysis (HD) patients. The rates of BSI among HD patients vary and are influenced by local patient and pathogen characteristics.
Miri Schamroth Pravda, Yasmin Maor, Konstantin Brodsky, Anna Katkov, Relu Cernes, Nili Schamroth Pravda, Milena Tocut, Iris Zohar, Arie Soroksky, Leonid Feldman   +9 more
doaj   +1 more source

A high force of Plasmodium vivax blood-stage infection drives the rapid acquisition of immunity in Papua New Guinean children [PDF]

, 2013
When both parasite species are co-endemic, Plasmodium vivax incidence peaks in younger children compared to P. falciparum. To identify differences in the number of blood stage infections of these species and its potential link to acquisition of immunity,
Speed, Terence P., Ingrid Felger (92160), Kiniboro, B, Mueller Ivo, Kathryn L Colborn, Koepfli, Cristian, Terence P. Speed (132229), Speed Terence P., Koepfli, C, Cristian Koepfli, Felger Ingrid, Felger, Ingrid, Kiniboro, Benson, Terence P Speed, Kiniboro Benson, Ingrid Felger, Peter M. Siba (136849), Ivo Mueller (46609), Felger, I, Enmoore Lin, Lin Enmoore, Mueller, Ivo, Benson Kiniboro (191309), Ivo Mueller, Enmoore Lin (137888), Koepfli Cristian, Lin, Enmoore, Lin, E, Kathryn L. Colborn (454997), Colborn Kathryn L., Siba Peter M., Speed, TP, Mueller, I, Colborn, Kathryn L., Siba, PM, Siba, Peter M., Colborn, KL, Peter M Siba, Cristian Koepfli (191306), Benson Kiniboro   +39 more
core   +2 more sources

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

Advanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang, Yangfan Huo, Jin Liu, Sida Liu, Minghai Ma, Hao Guo, Yuanquan Zhang, Xing Li, Xiao Liang, Jiawei Xiu, Ying Sun, Lijun Huang, Xiaolong Yan, Weiwei Wu, Lei Wang   +14 more
wiley   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Public Event: Stream Sessions

, 2017
The first Stream Session will be on Wednesday, March 29 from 2:00-4:00 pm at the conference room at the Burnaby Campus (8652). Stream Sessions are intended to be a colloquium where graduate students are invited to present their ideas to fellow students ...
Ackerley, Christine Rose
core   +1 more source