Results 241 to 250 of about 42,062 (291)
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Advanced Drug Delivery Reviews, 2000
Red cell substitutes are a group of oxygen carriers designed to temporarily replace transfused blood. Each product is unique in its limitations and advantages. Research and development has been slow because of the far-reaching consequences of replacing an oxygen carrier outside of the red cell.
R M Winslow
exaly +7 more sources
Red cell substitutes are a group of oxygen carriers designed to temporarily replace transfused blood. Each product is unique in its limitations and advantages. Research and development has been slow because of the far-reaching consequences of replacing an oxygen carrier outside of the red cell.
R M Winslow
exaly +7 more sources
Annual Review of Biomedical Engineering, 2014
The toxic side effects of early generations of red blood cell substitutes have stimulated development of more safe and efficacious high-molecular-weight polymerized hemoglobins, poly(ethylene glycol)-conjugated hemoglobins, and vesicle-encapsulated hemoglobins.
André F Palmer
exaly +3 more sources
The toxic side effects of early generations of red blood cell substitutes have stimulated development of more safe and efficacious high-molecular-weight polymerized hemoglobins, poly(ethylene glycol)-conjugated hemoglobins, and vesicle-encapsulated hemoglobins.
André F Palmer
exaly +3 more sources
Current Opinion in Anaesthesiology, 2004
Risk of disease transmission and limitations in the ability to transfuse in the prehospital or combat setting have stimulated research in the field of oxygen therapeutics. Several products have completed safety trials and are presently undergoing investigation for their efficacy.
Fahim A, Habib, Stephen M, Cohn
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Risk of disease transmission and limitations in the ability to transfuse in the prehospital or combat setting have stimulated research in the field of oxygen therapeutics. Several products have completed safety trials and are presently undergoing investigation for their efficacy.
Fahim A, Habib, Stephen M, Cohn
openaire +2 more sources
Blood Transfusion or Blood Substitution?
Vox Sanguinis, 1986Abstract. Blood transfusion has become a universally accepted, life‐saving procedure in modern clinical medicine. In addition, specific blood fractions are widely used in the therapeutic treatment of haematological disorders. Problems are, however, encountered in conventional transfusion practice and in the clinical use of blood components.
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Perfluorocarbon blood substitutes
Critical Reviews in Oncology/Hematology, 1987The salient physicochemical properties of the fluorocarbons are briefly reviewed, including their solubility for the physiologically important gases and their properties relevant to formulation (nonmiscibility with water). The preparations used to date are described, including their properties and compositions, with some comment about the available ...
George P. Biro +2 more
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Transfusion Science, 1992
The problem of transmissibility of human immunodeficiency virus by blood transfusion’ and the generally increased awareness of transfusiontransmitted diseases2 have recently resulted in a resurgence of interest in artificial blood substitutes. Among these, we have to distinguish between plasma substitutes and red blood cell substitutes.
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The problem of transmissibility of human immunodeficiency virus by blood transfusion’ and the generally increased awareness of transfusiontransmitted diseases2 have recently resulted in a resurgence of interest in artificial blood substitutes. Among these, we have to distinguish between plasma substitutes and red blood cell substitutes.
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Hemodilution and Blood Substitutes
Artificial Cells, Blood Substitutes, and Biotechnology, 1994The primary consequence of the substitution or replacement of blood with a surrogate is the dilution of the original constituents. This hemodilution produces systemic and microvascular phenomena that underlie all forms of blood replacement and provides a physiological reference for comparison for blood substitutes.
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Critical Care Clinics, 2009
There is an ongoing need for a red cell substitute, an oxygen-carrying solution to use primarily as a bridge until red cells are available. The replacement of oxygen-carrying capacity has driven the field of research, primarily with the development of hemoglobin-based oxygen carriers, but they are less than ideal.
openaire +2 more sources
There is an ongoing need for a red cell substitute, an oxygen-carrying solution to use primarily as a bridge until red cells are available. The replacement of oxygen-carrying capacity has driven the field of research, primarily with the development of hemoglobin-based oxygen carriers, but they are less than ideal.
openaire +2 more sources