Results 41 to 50 of about 39,946 (252)

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Sustitutos de la sangre Blood substitutes

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2001
Los sustitutos de la sangre, muchos de ellos aún en desarrollo, pueden constituir en un futuro no muy lejano un importante medio terapéutico, capaz de sustituir el empleo de componentes de la sangre alogénica, lo que evadiría los riesgos que el empleo de
María Elena Alfonso Valdés<a name=autor></a>
doaj  

The Reaction of Oxy Hemoglobin with Nitrite: Mechanism, Antioxidant-Modulated Effect, and Implications for Blood Substitute Evaluation

Molecules, 2018
The autocatalytic reaction between nitrite and the oxy form of globins involves free radicals. For myoglobin (Mb), an initial binding of nitrite to the iron-coordinated oxygen molecule was proposed; the resulting ferrous-peroxynitrate species was not ...
Denisa Hathazi, Florina Scurtu, Cristina Bischin, Augustin Mot, Amr A. A. Attia, Jacob Kongsted, Radu Silaghi-Dumitrescu   +6 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

How Synthetic Biology and Metabolic Engineering Can Boost the Generation of Artificial Blood Using Microbial Production Hosts

Frontiers in Bioengineering and Biotechnology, 2018
Hemoglobin is an essential protein to the human body as it transports oxygen to organs and tissues through the bloodstream (Looker et al., 1992). In recent years, there has been an increasing concern regarding the global supply of this vital protein, as ...
August T. Frost, Irene H. Jacobsen, Andreas Worberg, José L. Martínez   +3 more
doaj   +1 more source

Pilot study on novel blood containers with alternative plasticizers for red cell concentrate storage. [PDF]

PLoS ONE, 2017
Di (2-ethylhexyl) phthalate (DEHP), a typical plasticizer used for polyvinyl chloride (PVC) blood containers, is eluted from the blood containers and exerts protective effects on red blood cells.
Yuki Morishita, Yusuke Nomura, Chie Fukui, Tsuyoshi Kawakami, Toshiyuki Ikeda, Tomokazu Mukai, Toshiyasu Yuba, Ken-Ichi Inamura, Hisatoki Yamaoka, Ken-Ichi Miyazaki, Hitoshi Okazaki, Yuji Haishima   +11 more
doaj   +1 more source

T2* Magnetic Resonance Imaging Uncovers Hemosiderin Burden in Pediatric Hemophilia: A Call for Sensitive Imaging Biomarkers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia, Tarique Hussain, Jeanne Dillenbeck, Matthew Hammer, Annette von Drygalski, Guy Young, Ayesha Zia   +6 more
wiley   +1 more source

Expanded Access Use of Sanguinate Saves Lives: Over 100 Cases Including 14 Previously Published Cases

Anesthesia Research
Background: PP-007 (SANGUINATE®, PEGylated carboxyhemoglobin, bovine) is under development to treat conditions of ischemia/hypoxia. Hemorrhagic/hypovolemic shock (H/HVS) becomes a life-threatening comorbidity due in part to hypotension and hypoxia. Blood
Jonathan S. Jahr, Ronald Jubin, Zhen Mei, Joseph Giessinger, Rubie Choi, Abe Abuchowski   +5 more
doaj   +1 more source

Management of patients who refuse blood transfusion

Indian Journal of Anaesthesia, 2014
A small group of people belonging to a certain religion, called Jehovah′s witness do not accept blood transfusion or blood products, based on biblical readings.
N Kiran Chand, H Bala Subramanya, G Venkateswara Rao   +2 more
doaj   +1 more source