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Blood substitutes- the polyheme trials
McGill Journal of Medicine, 2008 N ...
Sameer S Apte
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 Hemoglobin-vesicles (HbVs) are artificial oxygen carriers encapsulating purified and concentrated hemoglobin solution in phospholipid vesicles (liposomes) and their safety and efficacy as a transfusion alternative have been evaluated.
Hiromi Sakai, Cassandra Leong
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Journal of Functional Biomaterials, 2017 Hemoglobin (Hb) is the most abundant protein in whole blood. This fact implies that the oxygen binding and releasing function of Hb is the most vital for sustaining life.
Hiromi Sakai
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Oxidation reactions of cellular and acellular hemoglobins: Implications for human health
Frontiers in Medical Technology, 2022 Oxygen reversibly binds to the redox active iron, a transition metal in human Hemoglobin (Hb), which subsequently undergoes oxidation in air. This process is akin to iron rusting in non-biological systems.
Abdu I. Alayash
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Canadian Anaesthetists’ Society Journal, 1975 Substitutes for whole blood include blood fractions such as plasma, serum albumin and other fluids of various kinds which are not derived from blood but are used as plasma volume expanders; these, include the usual crystaloid intravenous solutions.
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Progress in the search for blood substitutes, part 1 Preparations currently used in haemotherapy as an indicator of new drug development [PDF]
Farmacja Polska, 2022 The hospital pharmacy in polish conditions, rarely participates in the logistic process related to the transport, storage and administration of blood, however, it is involved in supplying the hospital with a variety of blood products and blood ...
Waldemar Grzegorzewski +4 more
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Pharmaceutics, 2021 Every day, thousands of patients receive erythrocyte concentrates (ECs). They are indispensable for modern medicine, despite their limited resource. Artificial oxygen carriers (AOCs) represent a promising approach to reduce the need for ECs.
Sarah Hester +3 more
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Revista Brasileira de Hematologia e Hemoterapia, 2007 Os procedimentos necessários para redução de efeitos adversos associados à transfusão de sangue, em especial aqueles decorrentes da transmissão de agentes infecciosos e da aloimunização leucócito-mediada têm impacto nos custos de produção de ...
Marcia Cristina Z. Novaretti
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Artif. Cells Blood Substit. Biotechnol.
, 2010 The gelatin plasma substitute is often polydisperse and heterogenous, making it difficult to determine the elimination rate and half-life in the body.
Wang, Yinjue +11 more
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Current Status and Future of Artificial Blood- Focusing on Red Blood Cell Substitutes [PDF]
, 2009 Blood substitutes, especially red blood cell (RBC) substitutes, have been developed for the past five decades and have several advantages over allogenic packed RBCs, including a prolonged half-life, lack of a cross-matching requirement, and minimal ...
김종훈, 이기영
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