Resuscitation After Hemorrhagic Shock in the Microcirculation: Targeting Optimal Oxygen Delivery in the Design of Artificial Blood Substitutes [PDF]
Frontiers in Medicine, 2020 Microcirculatory preservation is essential for patient recovery from hemorrhagic shock. In hemorrhagic shock, microcirculatory flow and pressure are greatly reduced, creating an oxygen debt that may eventually become irreversible.
Carlos Munoz +5 more
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Blood Substitutes Used in Dentistry and OMFS: Systematic Review [PDF]
Journal of Pharmacy and Bioallied SciencesPerioperative blood loss during dental and oral and maxillofacial surgical (OMFS) procedures often necessitates red blood cell (RBC) transfusion. However, associated risks, cost, and supply limitations have prompted the exploration of alternatives and ...
Rajshree Borah +6 more
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Research progress and future of red blood cell substitutes
Zhongguo shuxue zazhi, 2022 This paper briefly reviewed blood substitutes, focusing on the background, history of research and development(R&D), types, functions, characteristics, the indications that will be mainly targeted in clinical, and their special status and role in the ...
Jiaxin LIU, Chengmin YANG
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Artificial Blood Substitutes: First Steps on the Long Route to Clinical Utility [PDF]
Clinical Medicine Insights: Blood Disorders, 2016 The 21st century is challenging for human beings. Increased population growth, population aging, generation of new infectious agents, and natural disasters are some threatening factors for the current state of blood transfusion.
Samira Moradi +2 more
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BLOOD AND BLOOD SUBSTITUTES [PDF]
British Journal of Anaesthesia, 1977 A, Doenicke, B, Grote, W, Lorenz
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Synthetic oxygen carriers as substitutes of red blood cells for blood transfusion [PDF]
RSC AdvancesThe search for an efficacious blood substitute has remained a persistent challenge for more than a century. Despite extensive efforts to develop synthetic oxygen carriers, no broadly approved alternative to human blood has yet been realized.
Yinghong Shi +7 more
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Blood substitutes: Basic science, translational studies and clinical trials [PDF]
Frontiers in Medical Technology, 2022 Jonathan S. Jahr
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Comparative effects of salt substitutes on blood pressure, cardiovascular events and mortality: a systematic review and network meta-analysis [PDF]
BMC MedicineBackground Hypertension is a major risk factor for cardiovascular disease. Salt substitutes may reduce sodium intake while maintaining palatability, but comparative effects across formulations remain uncertain.
Honghao Lai +13 more
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Artificial Cells, Nanomedicine, and Biotechnology, 2019 Hemoglobin-vesicles (HbVs) are artificial oxygen carriers encapsulating purified and concentrated hemoglobin solution in phospholipid vesicles (liposomes) and their safety and efficacy as a transfusion alternative have been evaluated.
Hiromi Sakai, Cassandra Leong
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Bad Blood: Cons of Synthetic Blood Substitutes
, 2012 In recent years scientists have been attempting to develop synthetic blood substitutes in order to counter both the shortage in donor blood and the problems associated with infection and disease during allogeneic transfusion. Most attempts have been made
Guerra, Andres
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