Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao +8 more
wiley +1 more source
Investigating the Effect of eradication of <i>Helicobacter Pylori</i> Infection in Controlling Blood Sugar in Diabetic Patients. [PDF]
Fahad MA.
europepmc +1 more source
Comparison of Glucometry and Venous Blood Sugar Results in Diabetic Patients Undergoing Open Heart Surgery with Hemodynamic Instability [PDF]
Moosa Sajjadi +3 more
openalex +1 more source
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia +11 more
wiley +1 more source
Association of Anthropometric Parameters with Elevated Fasting Blood Sugar among Filipino Adults Aged 18-65 years in Highly Urbanized Cities in the Philippines. [PDF]
Rama-Sabandal RLCM +7 more
europepmc +1 more source
Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang +22 more
wiley +1 more source
Supervised Machine Learning-Based Models for Predicting Raised Blood Sugar. [PDF]
Owess MM, Owda AY, Owda M, Massad S.
europepmc +1 more source
Machine learning‐assisted surface‐enhanced Raman spectroscopy analysis of exosomal sialic acid for ovarian cancer diagnosis, as well as independent monitoring of exosomal sialic acid expression levels across different treatment periods, reveals a potential correlation with treatment response.
Lili Cong +6 more
wiley +1 more source
Are diabetes and blood sugar control associated with the diagnosis of eye diseases? An English prospective observational study of glaucoma, diabetic eye disease, macular degeneration and cataract diagnosis trajectories in older age. [PDF]
Lin C, Jivraj S.
europepmc +1 more source

