Results 31 to 40 of about 22,485 (145)

Perioperative Transfusion Trigger Score Versus Restrictive Transfusion in Older Non‐Cardiac Surgery Patients: A Multicenter Randomized Controlled Trial

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang, Lijuan Bai, Guizhen Yang, Zhuo Chen, Yujia Wei, Yanxia Wei, Yuting Lv, Zehan Huang, Yanjuan Huang, Kejian Lu   +9 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

Transplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez, Carla Niveyro, Pedro Andrés Villalba Apestegui, Victoria Isabel Martin, Lucila María Compañy Kec, María Cynthia Tomasino, Mariana del Carmen del Marull, Haydee Ingrid Bernard, Claudia Patricia Lorena Fernández, Flavia Marcela Pelech, Maria Fernanda Tosin, María Fernanda González‐Hobecker, Karen Beatrice Duranona, Angela Daiana Jara, Justus Cornely, Oliver A. Cornely, Jon Salmanton‐García   +16 more
wiley   +1 more source

Temporal dynamics of immune effector cell‐associated haematotoxicity: Linking early and late cytopenias after chimeric antigen receptor T cells

British Journal of Haematology, EarlyView.
Malvina Bichon, Roch Houot, Mana Alshehri, Guillaume Manson, Faustine Lhomme, Samuel Vic   +5 more
wiley   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

AABB survey on directed blood donation practices

Transfusion, EarlyView.
Abstract Background Standardized guidance regarding the processes for collecting directed blood donations (DBD) is lacking, leading to variable practices. This study assessed laboratory, clinical, and charging practices for DBD collection in the United States and Canada. Study Design and Methods An electronic survey was distributed to United States and
Nabiha H. Saifee, Emily Coberly, Brian D. Adkins, Louise Helander, Nancy Robitaille, Laura K. Dilly, Lani Lieberman   +6 more
wiley   +1 more source

Usefulness of pegfilgrastim for allogeneic peripheral blood stem cell collection from healthy donors

Transfusion, EarlyView.
Abstract Background Granulocyte colony‐stimulating factor (G‐CSF)‐based mobilization is essential for peripheral blood stem cell (PBSC) collection for allogeneic transplantation. Conventional daily G‐CSF requires repeated dosing and dose adjustment and often necessitates leukapheresis over multiple consecutive days, increasing donor burden. Single‐dose
Tomoshige Shimizu, Tomoyasu Jo, Noriyoshi Yoshinaga, Takashi Sakamoto, Hiroyuki Matsui, Toshio Kitawaki, Junya Kanda, Momoko Nishikori, Kouhei Yamashita, Miki Nagao, Akifumi Takaori‐Kondo, Yasuyuki Arai   +11 more
wiley   +1 more source

Red blood cells stored in anticoagulant versus additive solution for large volume transfusions in pediatric patients undergoing cardiopulmonary bypass

Transfusion, EarlyView.
Abstract Background The safety of red blood cells (RBCs) in additive solutions (AS) for large‐volume transfusion (LVT) in pediatrics remains understudied. This study examines the laboratory and clinical impact of CPD‐stored products versus CP2D/AS‐3 products in pediatric patients receiving LVT during cardiac surgery.
Nabiha H. Saifee, Meghan Delaney
wiley   +1 more source

Venous and arterial thrombosis following extracorporeal photopheresis: A descriptive cohort study using a federated electronic health record network

Transfusion, EarlyView.
Abstract Background In 2018, the FDA reported VTE events in patients undergoing ECP, but these reports lacked a population‐level denominator to contextualize the risk against the known baseline thrombotic burden of the underlying conditions. Study Design and Methods We conducted a descriptive retrospective cohort study using the TriNetX federated EHR ...
Caitlin Raymond
wiley   +1 more source

HIV incidence and correlates of incident infection among Brazilian blood donors following adoption of individual donor assessment

Vox Sanguinis, EarlyView.
Abstract Background and Objectives In 2020, Brazil implemented individual donor assessment (IDA), expanding eligibility to include individuals previously deferred, such as men who have sex with men (MSM). We assessed human immunodeficiency virus (HIV) incidence and correlates of incident infection among blood donors following this policy change ...
Renata Buccheri, Eduard Grebe, Donald E. Warden, Carolina Miranda, Ligia Capuani, Cecilia S. Alencar, Luiz Amorim, Cesar de Almeida‐Neto, Maisa Ribeiro, Paula Loureiro, Nelson Fraiji, Clara Di Germanio, Leilani Montalvo, Jennifer Leddy, Mars Stone, Ester C. Sabino, Brian Custer, the Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P)   +17 more
wiley   +1 more source