Results 41 to 50 of about 2,239,398 (235)

Analysis of factors affecting length of hospital stay after Sun's procedure in patients with type A aortic coarctation based on LASSO regression

open access: yesZhongguo shuxue zazhi, 2023
Objective To investigate the factors affecting the length of hospitalization after the Sun's procedure in patients with type A aortic coarctation. Methods From January 2018 to June 2023, the clinical data, related laboratory indicators and perioperative ...
Hongliang ZHANG   +4 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Autologous Blood Transfusion in Total Hip Arthroplasty

open access: yesJournal of Orthopaedic Surgery, 2004
Purpose. To determine the possibility of avoiding homologous blood transfusion during total hip arthroplasty, and to clarify the problems associated with autologous blood transfusion. Methods. A total of 253 patients received autologous blood transfusion
K Yamamoto   +3 more
doaj   +1 more source

EVALUATION OF QUALITATIVE AND QUANTITATIVE INDICATORS OF SUBSTITUTIONARY TRANSFUSION THERAPY IN DIFFERENT TYPES OF HEMATOPOIETIC STEM CELL TRANSPLANTATION

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Relevance. Hematopoietic stem cell transplantation (HSCT) is one of methods to care patients with malignancy, hematologic and hereditary diseases; in most cases, it requires prolonged and massive substitutionary transfusion therapy.
M. A. Kucher   +5 more
doaj   +1 more source

Fresh autologous blood transfusion reverses erythrocytes damage by reducing oxidative stress via promoting mitochondrial metabolism and M2 macrophages polarization

open access: yesArchives of Medical Science, 2022
Introduction Systemic inflammatory and immunosuppressive incidents constitute a significant hallmark of the adverse effects of RBC transfusion on red blood cells. These adverse side effects are seemingly associated with old blood transfusions; therefore,
Jia-Ming Xu   +7 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

open access: yesAdvanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung   +39 more
wiley   +1 more source

Blood transfusion practices in cardiac anaesthesia

open access: yesIndian Journal of Anaesthesia, 2014
The primary reasons for blood transfusion in cardiac surgery are to correct anaemia and to improve tissue oxygen delivery. However, there is a considerable debate regarding the actual transfusion trigger at which the benefits of transfusion overweight ...
Hanumantha Rao Mangu   +2 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Autologous Transfusion after Total Knee Arthroplasty

open access: yesPakistan Armed Forces Medical Journal, 2023
Objective: To determine whether the blood lost in total knee arthroplasty surgery can be salvaged and reused using the autotransfusion technique without adverse effects and need more blood requirement. Study Design: Prospective longitudinal study.
Fayyaz Ahmed Orfi   +4 more
doaj   +1 more source

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