Results 41 to 50 of about 21,882 (168)

Bionic nanobombs target nasopharyngeal carcinoma to enhance the efficacy of chemoradiotherapy by destroying DNA damage repair systems

VIEW, EarlyView.
A bionic nanomedicine system with core–shell structure (Nm‐pAu/CP/KU) was constructed. PEGylated gold nanoparticles (pAu) were loaded with cisplatin (CP) and a radiochemotherapy sensitizer (KU‐60019) to form the core pAu/CP/KU, and homologous nasopharyngeal carcinoma cell membrane vesicles (Nm) were used as the shell.
Junhua Zhang, Xinying Xiang, Xinmin Nie, Jian Li, Rong Gui   +4 more
wiley   +1 more source

Autologous Blood Reinfusion in Patients Undergoing Bilateral Total Hip Arthroplasty

Journal of Orthopaedic Surgery, 2011
Purpose. To compare the rate and unit of allogeneic blood transfusion in one-stage bilateral total hip arthroplasty (THA) in patients with and without autologous blood reinfusion. Methods. Records of a consecutive series of 43 men and 33 women aged 25 to
Albert O Gee, Jonathan P Garino, Gwo-Chin Lee   +2 more
doaj   +1 more source

Regenerative Medicine Advancements: A Systematic Review on the Combinatory Effect of Platelet-Rich Plasma/Fibrin and Collagen. [PDF]

Int J Biomater
Background The regeneration of injured tissues remains a major clinical challenge. Among emerging biomaterials, collagen with platelet‐rich plasma (PRP) or platelet‐rich fibrin (PRF) showed promising outcomes, individually and in combination. Objective To systematically review clinical evidence on the efficacy, applications, and safety of PRP/PRF and ...
Gallo N, Kodra C, Rocco D, Saponaro C, Sannino A, Salvatore L.   +5 more
europepmc   +2 more sources

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao, Shen Zhan, Gang Fu, Shanshan Guo, Lifang Liu, Wei Liu, Guanghui Xiao, Yuzhu Wang, Lihong Zhang   +8 more
wiley   +1 more source

Over‐Transfusion and Unnecessary Transfusion Following Post‐Partum Haemorrhage at Te Toka Tumai Auckland Hospital

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Blood transfusion is an important treatment for obstetric haemorrhage. Transfusion also engenders significant short and long‐term risks. Ensuring blood products are only given when necessary is a priority in improving outcomes. Aims To describe the population transfused at a single unit in New Zealand and identify the proportion of ...
J. Stefanus Grobler, Lynn C. Sadler, John Thompson, Matthew Drake, Beatrice Treadwell, Jenny McDougall, Meghan G. Hill   +6 more
wiley   +1 more source

Opportunities for improving platelet transfusion practice: A large retrospective audit across 22 hospitals

British Journal of Haematology, EarlyView.
Summary Despite evidence‐based guidelines to inform platelet transfusion practice, unnecessary platelet transfusion persists. We performed a multicentre retrospective analysis of adults admitted to general medicine, subspecialty medicine and critical care from 1 January 2017 to 30 June 2022.
Sarah Ryan, Yang Liu, Sheharyar Raza, Anne Loeffler, Nicole Relke, Nadia Gabarin, Malcolm Risk, Phuong Uyen Nguyen, Na Li, Amol Verma, Fahad Razak, Keyvan Karkouti, Janique Dyba, Donald Arnold, Jeannie Callum   +14 more
wiley   +1 more source

Intraoperative cell salvage for obstetrics: a prospective randomized controlled clinical trial

BMC Pregnancy and Childbirth, 2020
Background The latest basic studies and clinical evidence have confirmed the safety and efficacy of intraoperative autologous blood cell transfusion in cardiac surgery and orthopaedics.
Ye Liu, Xiaoguang Li, Xiangming Che, Guosheng Zhao, Mingjun Xu   +4 more
doaj   +1 more source

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches

Developing World Bioethics, EarlyView.
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley   +1 more source

Impact of Preanalytical Sample Preparation on the Recovery Rate of Cryopreserved Allogeneic Hematopoietic Stem Cells

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Cryopreservation of peripheral‐blood‐derived hematopoietic stem and progenitor cells (PBSCs) has been used for decades, primarily for autologous transplantation. Now, in the era of new cellular therapies, the cryopreservation of allogeneic PBSCs may also become relevant.
Philipp Blüm, Christina Glas, Karen Bieback, Sabine Kayser, Harald Klüter, Patrick Wuchter   +5 more
wiley   +1 more source

Perioperative Blood Transfusion as a Significant Predictor of Biochemical Recurrence and Survival after Radical Prostatectomy in Patients with Prostate Cancer. [PDF]

PLoS ONE, 2016
PURPOSE:There have been conflicting reports regarding the association of perioperative blood transfusion (PBT) with oncologic outcomes including recurrence rates and survival outcomes in prostate cancer.
Jung Kwon Kim, Hyung Suk Kim, Juhyun Park, Chang Wook Jeong, Ja Hyeon Ku, Hyun Hoe Kim, Cheol Kwak   +6 more
doaj   +1 more source