Results 121 to 130 of about 362,610 (315)

Red blood cell alloantibodies in patients with thalassemia major referred to the blood transfusion center of Golestan province, Iran [PDF]

open access: yesMedical Laboratory Journal
Background: One of the major complications in thalassemia patients is alloimmunization, which occurs when the patient produces antibodies against transfused Red Blood Cells (RBCs). In the present study, the frequency of alloantibodies was investigated in
Seyed Sadegh Baniaghil   +2 more
doaj  

INCIDENCE OF Rh ANTI-E AND ANTI-c PRODUCTION AMONG JAPANESE AFTER BLOOD TRANSFUSION

open access: yes, 1988
The incidence of Rh anti-E antibody production due to blood transfusion in the patients who were Rh E negative and were transfused with more than one unit (200 ml) of E positive red blood cells was examined.
Fumio, KOMATSU
core   +1 more source

Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim   +13 more
wiley   +1 more source

Therapeutic Outcomes in VEXAS Syndrome: A Multicenter Comparative Cohort of Allogeneic Hematopoietic Stem Cell Transplantation and Hypomethylating Agents

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Hypomethylating agents (HMA) and allogeneic hematopoietic stem cell transplantation (alloHSCT) have both demonstrated remissions in VEXAS; however, comparative data is lacking. We conducted a multicenter, retrospective analysis of 66 patients diagnosed with VEXAS syndrome treated with HMA (n = 35) or alloHSCT (n = 31). Baseline characteristics
Saubia Fathima   +48 more
wiley   +1 more source

HEV in Blood Donors in Switzerland: The Route to Safe Blood Products

open access: yesPathogens
The hepatitis E virus (HEV) is an emerging infectious disease with zoonotic potential, causing acute hepatitis in humans. Infections in healthy individuals are often acute, self-limiting and asymptomatic, thus leading to the underdiagnosis of HEV ...
Mauro Serricchio   +4 more
doaj   +1 more source

Blood transfusion [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2020
openaire   +2 more sources

Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the 'Seville Document'

open access: yes, 2017
Summary of recommendations on alternatives to reduce allogeneic blood transfusion (in descending order of strength)..
Páramo Fernández, José A.   +12 more
core   +1 more source

Laboratory analyses for evaluation of platelet disorders and platelet concentrates

open access: yes, 2006
High quality of platelet analytics requires specialized knowledge and skills. It was applied to analyze platelet activation and aggregation responses in a prospective controlled study of patients with Finnish type of amyloidosis.
Javela, Kaija
core  

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Full-length haplotype reconstruction of CD36 by long-read sequencing: uncovers a novel structural variant

open access: yesBMC Genomics
Purpose CD36 deficiency predisposes to fetal/neonatal alloimmune thrombocytopenia (FNAIT) and platelet transfusion refractoriness (PTR), yet its genetic architecture remains incompletely understood.
Shuang Liang   +9 more
doaj   +1 more source

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