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Gut microbiota were altered with platelet count and red blood cell count in immune thrombocytopenia patients with different treatments

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The gut microbiome is clearly linked to the development of various autoimmune diseases, however, its association with immune thrombocytopenia (ITP) is less well understood. The current study collected 73 samples, including 36 from healthy individuals and
Xue Rui   +5 more
doaj   +1 more source

Psychometric characteristics of the Revised Illness Perception Questionnaire (IPQ-R) in adults with sickle cell disease

open access: yesHealth Psychology and Behavioral Medicine, 2022
Objective Sickle cell disease (SCD) is the most frequent monogenic disease worldwide. Psychological and behavioural factors are often reported as playing a significant role in predicting SCD health outcomes.
Damien Oudin Doglioni   +3 more
doaj   +1 more source

Determining a critical threshold for G6PD activity below which red blood cell response to oxidative stress is poor

open access: yesMalaria Journal, 2020
Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme disorder in the world. Its main function is to generate NADPH that is required for anti-oxidative pathway in the cells especially in red blood cells (RBC).
Maria Swastika   +4 more
doaj   +1 more source

Towards manufactured red blood cells for the treatment of inherited anemia

open access: yesHaematologica, 2021
Patients with inherited anemia and hemoglobinopathies (such as sickle cell disease and β-thalassemia) are treated with red blood cell (RBC) transfusions to alleviate their symptoms.
Stephanie Pellegrin   +2 more
doaj   +1 more source

Automated image analysis detects aging in clinical-grade mesenchymal stromal cell cultures

open access: yesStem Cell Research & Therapy, 2018
Background Senescent cells are undesirable in cell therapy products due to reduced therapeutic activity and risk of aberrant cellular effects, and methods for assessing senescence are needed. Early-passage mesenchymal stromal cells (MSCs) are known to be
S. Oja   +4 more
doaj   +1 more source

The Red Blood Cells on the Move! [PDF]

open access: yesFrontiers in Physiology, 2018
Following the steps of the founders of modern red blood cell (RBC) research (e.g., Ørskov, 1935; Wilbrandt, 1937; Cohn and Cohn, 1939; Ponder, 1948; Pauling et al., 1949), we answer to the growing need of a platform to share and discuss the new findings, argue and move forward in our understanding of these amazing cells.
Bogdanova, Anna, Kaestner, Lars
openaire   +5 more sources

THE AGGLUTINATION OF RED BLOOD CELLS [PDF]

open access: yesJournal of General Physiology, 1924
1. Unsensitized sheep cells suspended in sugar solutions are agglutinated by electrolytes whenever the potential is depressed to 6 millivolts or less, except in the case of MgCl2 or CaCl2. 2. With these salts no agglutination occurs although there is practically no potential. The presence of these salts prevents acid agglutination.
J H, Northrop, J, Freund
openaire   +2 more sources

Shear-Stress-Gradient and Oxygen-Gradient Ektacytometry in Sickle Cell Patients at Steady State and during Vaso-Occlusive Crises

open access: yesCells, 2022
Oxygen gradient ektacytometry (oxygenscan) measures the changes in red blood cell (RBC) deformability in normoxia and during deoxygenation. We investigated the changes in RBC deformability, measured by both oxygenscan and classical shear-stress-gradient ...
Camille Boisson   +12 more
doaj   +1 more source

Red blood cells in thrombosis [PDF]

open access: yesBlood, 2017
Abstract Red blood cells (RBCs) have historically been considered passive bystanders in thrombosis. However, clinical and epidemiological studies have associated quantitative and qualitative abnormalities in RBCs, including altered hematocrit, sickle cell disease, thalassemia, hemolytic anemias, and malaria, with both arterial and venous
James R. Byrnes, Alisa S. Wolberg
openaire   +2 more sources

Erythrocyte depletion from bone marrow: performance evaluation after 50 clinical-scale depletions with Spectra Optia BMC

open access: yesJournal of Translational Medicine, 2017
Background Red blood cell (RBC) depletion is a standard graft manipulation technique for ABO-incompatible bone marrow (BM) transplants. The BM processing module for Spectra Optia, “BMC”, was previously introduced.
Soo-Zin Kim-Wanner   +11 more
doaj   +1 more source

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