Results 31 to 40 of about 1,241,346 (218)

All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD [PDF]

, 2011
Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic appears to be waning, there is much concern that vCJD infection may be perpetuated in humans by the ...
Smith, Antony, Ian R. MacGregor, Groschup, Martin H., Hunter, N., Hunter, Nora, Prowse, C.V., Tan, B.C., Hornsey, V.S., Boon Chin Tan, Sandra McCutcheon, Jean C Manson, Antony Smith, E. Fiona Houston, Jean C. Manson, Alejo-Blanco, Richard, Manson, J.C., Tan, Boon Chin, Turner Marc, Manson, Jean C., Houston E. Fiona, Alejo Blanco, A.R., Turner, Marc, Groschup Martin H., MacGregor, Ian R., Houston, Fiona, Christopher V Prowse, Turner, M., E Fiona Houston, Alejo Blanco Anthony Richard, Groschup, M.H., Martin H Groschup, Smith Antony, de Wolf, C., Christopher V. Prowse, Hunter Nora, Prowse, Christopher V., Christopher de Wolf, Anthony Richard Alejo Blanco, MacGregor Ian R., de Wolf Christopher, Marc Turner, de Wolf, Christopher, Valerie S. Hornsey, Smith, A., Manson Jean C., Prowse Christopher V., Ian R MacGregor, Prowse, C. V., Hornsey, Valerie S., McCutcheon Sandra, MacGregor, I.R., McCutcheon, Sandra, Nora Hunter, Tan Boon Chin, Hornsey Valerie S., Martin H. Groschup, McCutcheon, S., Houston, E.F., Valerie S Hornsey   +58 more
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Red blood cell morphology [PDF]

International Journal of Laboratory Hematology, 2013
SummaryThe foundation of laboratory hematologic diagnosis is the complete blood count and review of the peripheral smear. In patients with anemia, the peripheral smear permits interpretation of diagnostically significant red blood cell (RBC) findings. These include assessment of RBC shape, size, color, inclusions, and arrangement.
openaire   +2 more sources

The association between intraoperative cell salvage and red blood cell transfusion in cardiac surgery – an observational study in a patient blood management centre

, 2021
Introduction: Cell salvage (CS) is an integral part of patient blood management (PBM) and aims to reduce allogeneic red blood cell (RBC) transfusion. Material and methods: This observational study analysed patients scheduled for elective cardiac surgery
Meybohm, Patrick, Linda Vo, Suma Choorapoikayil, Herrmann, Eva, Chris Triphaus, Andreas Winter, Judd, Leonie, Patrick Meybohm, Vo, Linda, Leonie Judd, Winter, Andreas, Triphaus, Chris, Kai Zacharowski, Neef, Vanessa, Zacharowski, Kai, Eva Herrmann, Vanessa Neef, Choorapoikayil, Suma   +17 more
core   +1 more source

Systematic literature review evaluating evidence and mechanisms of action for platelet-rich plasma as an antibacterial agent

Journal of Cardiothoracic Surgery, 2021
Platelet rich plasma or PRP is a supraphysiologic concentrate of platelets derived by centrifugation and separation of whole blood components. Along with platelets and plasma, PRP contains various cell types including white blood cells (WBC)/leukocytes ...
Dalip Sethi, Kimberly E. Martin, Sangeeta Shrotriya, Bethany L. Brown   +3 more
doaj   +1 more source

SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS

Journal of Hematology & Oncology, 2018
Background SF3B1 is a core component of splicing machinery. Mutations in SF3B1 are frequently found in myelodysplastic syndromes (MDS), particularly in patients with refractory anemia with ringed sideroblasts (RARS), characterized by isolated anemia ...
Yumin Huang, John Hale, Yaomei Wang, Wei Li, Shijie Zhang, Jieying Zhang, Huizhi Zhao, Xinhua Guo, Jing Liu, Hongxia Yan, Karina Yazdanbakhsh, Gang Huang, Christopher D. Hillyer, Narla Mohandas, Lixiang Chen, Ling Sun, Xiuli An   +16 more
doaj   +1 more source

Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype

Nature Communications, 2020
The molecular basis of the clinically important MAM blood group antigen present in most humans is unknown. We identify EMP3 as its encoding gene, establishing MAM as a new blood group system, and demonstrate the role of EMP3 in erythropoiesis through its
Nicole Thornton, Vanja Karamatic Crew, Louise Tilley, Carole A. Green, Chwen Ling Tay, Rebecca E. Griffiths, Belinda K. Singleton, Frances Spring, Piers Walser, Abdul Ghani Alattar, Benjamin Jones, Rosalind Laundy, Jill R. Storry, Mattias Möller, Lorna Wall, Richard Charlewood, Connie M. Westhoff, Christine Lomas-Francis, Vered Yahalom, Ute Feick, Axel Seltsam, Beate Mayer, Martin L. Olsson, David J. Anstee   +23 more
doaj   +1 more source

Osteoarthritis and analgesic consumption in haemochromatosis HFE C282Y homozygotes with normal or low iron parameters

Nature Communications
We studied 132,525 Danish general population individuals to examine whether risk of osteoarthritis and/or use of pain-relieving medication was increased in haemochromatosis C282Y homozygotes with normal or low plasma iron, transferrin saturation, or ...
Jens Helby, Mathis Mottelson, Stig Egil Bojesen, Børge Grønne Nordestgaard, Mikkel Faurschou, Jesper Petersen, Christina Ellervik, Marie Warny, Andreas Glenthøj   +8 more
doaj   +1 more source

Immunomonitoring of MSC-Treated GvHD Patients Reveals Only Moderate Potential for Response Prediction but Indicates Treatment Safety

Molecular Therapy: Methods & Clinical Development, 2018
Mesenchymal stromal cells (MSCs) are used as salvage therapy to treat steroid-refractory acute graft-versus-host disease (aGvHD). We studied the immunological response to MSC treatment in 16 aGvHD patients by assessing lymphocyte profiles and three ...
Joni Keto, Tanja Kaartinen, Urpu Salmenniemi, Johanna Castrén, Jukka Partanen, Arno Hänninen, Matti Korhonen, Kaarina Lähteenmäki, Maija Itälä-Remes, Johanna Nystedt   +9 more
doaj   +1 more source

A New Approach to Model Confined Suspensions Flows in Complex Networks: Application to Blood Flow [PDF]

, 2010
The modeling of blood flows confined in micro-channels or micro-capillary beds depends on the interactions between the cell-phase, plasma and the complex geometry of the network.
Plouraboué, Franck, Guibert, Romain, Fonta, Caroline   +2 more
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A pilot clinical phase II trial MemSID: Acute and durable changes of red blood cells of sickle cell disease patients on memantine treatment

eJHaem, 2020
An increase in abundance and activity of N‐methyl D‐aspartate receptors (NMDAR) was previously reported for red blood cells (RBCs) of sickle cell disease (SCD) patients. Increased Ca2+ uptake through the receptor supported dehydration and RBC damage.
Asya Mahkro, Inga Hegemann, Elena Seiler, Greta Simionato, Viviana Claveria, Nikolay Bogdanov, Clelia Sasselli, Paul Torgerson, Lars Kaestner, Markus G. Manz, Jeroen S. Goede, Max Gassmann, Anna Bogdanova   +12 more
doaj   +1 more source