Results 51 to 60 of about 1,241,346 (218)

Reversibility of red blood cell deformation [PDF]

Physical Review E, 2012
The ability of cells to undergo reversible shape changes is often crucial to their survival. For Red Blood Cells (RBCs), irreversible alteration of the cell shape and flexibility often causes anemia. Here we show theoretically that RBCs may react irreversibly to mechanical perturbations because of tensile stress in their cytoskeleton.
Zeitz, Maria, Sens, P.
openaire   +3 more sources

Glucose phosphate isomerase deficiency demasked by whole-genome sequencing: a case report

Journal of Medical Case Reports
Background Glucose-6-phosphate isomerase deficiency is a rare genetic disorder causing hereditary nonspherocytic hemolytic anemia. It is the second most common glycolytic enzymopathy in red blood cells.
Sissel Holme, Richard van Wijk, Andreas Ørslev Rasmussen, Jesper Petersen, Andreas Glenthøj   +4 more
doaj   +1 more source

Red cell transfusion triggers in critically ill patients:time for some new TRICCs?

, 2010
Current evidence suggests that critically ill patients tolerate anaemia well and that blood transfusions may increase the risk of adverse outcomes. Dr Sakr and colleagues present a contradictory analysis of a surgical ICU cohort, finding an association ...
Walsh, Timothy S; id_orcid, Timothy S Walsh   +1 more
core   +1 more source

Computational identification of phospho-tyrosine sub-networks related to acanthocyte generation in neuroacanthocytosis [PDF]

, 2012
Acanthocytes, abnormal thorny red blood cells (RBC), are one of the biological hallmarks of neuroacanthocytosis syndromes (NA), a group of rare hereditary neurodegenerative disorders.
Pantaleo, Antonella, Angela Siciliano, Jung, Hans H., Pantaleo A., Ruth H. Walker (184548), Dotti Maria Teresa, Bader B., Sara Mazzucco, Lucia De Franceschi (184533), Dotti, Maria Teresa, Tomelleri Carlo, Bader, B, Hans H. Jung (184555), Walker R. H., Mazzucco, Sara, Walker, R H, Scardoni, G, Danek, A, Carlo Tomelleri, Giovanni Scardoni, Sara Mazzucco (184565), Scardoni G, Bader Benedikt, Dotti, M T, Siciliano, Angela, Danek, Adrian, Tomelleri C, Lucia De Franceschi, Giovanni Scardoni (184538), Adrian Danek, Antonella Pantaleo (184574), Pantaleo, A, Pantaleo Antonella, Laudanna Carlo, Jung H. H., Benedikt Bader, Adrian Danek (4947), De Franceschi Lucia, Scardoni G., Siciliano A, Antonella Pantaleo, Danek Adrian, Tomelleri, Carlo, Hans H Jung, Jung, H H, Carlo Laudanna (184575), Laudanna C., Benedikt Bader (184560), Jung Hans H., DOTTI, MARIA, De Franceschi L, Jung HH, Tomelleri, C, Walker RH, De Franceschi, L, Pantaleo A, Laudanna, Carlo, Danek A, Carlo Laudanna, Siciliano, A, De Franceschi, Lucia, Maria Teresa Dotti (184569), Walker Ruth H., Scardoni, Giovanni, Ruth H Walker, Maria Teresa Dotti, Mazzucco Sara, Bader B, Scardoni Giovanni, Mazzucco, S, Dotti M. T., Laudanna, C, Angela Siciliano (184571), Siciliano Angela, Carlo Tomelleri (184542), Walker, Ruth H., Bader, Benedikt, Mazzucco S, Danek A.   +78 more
core   +1 more source

Liver X receptor agonist upregulates LPCAT3 in human aortic endothelial cells

Frontiers in Physiology
ObjectiveEndothelial cells (ECs) play an important role in tissue homeostasis. Recently, EC lipid metabolism has emerged as a regulator of EC function. The liver X receptors (LXRs) are involved in the transcriptional regulation of genes involved in lipid
Delphine Bousquet, Delphine Bousquet, Elie Nader, Elie Nader, Philippe Connes, Philippe Connes, Nicolas Guillot, Nicolas Guillot, Nicolas Guillot   +8 more
doaj   +1 more source

Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging

Blood Advances, 2018
: Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5.
T.R.L. Klei, D.Z. de Back, P.J. Asif, P.J.J.H. Verkuijlen, M. Veldthuis, P.C. Ligthart, J. Berghuis, E. Clifford, B.M. Beuger, T.K. van den Berg, R. van Zwieten, W. El Nemer, R. van Bruggen   +12 more
doaj   +1 more source

A Unique Epigenomic Landscape Defines Human Erythropoiesis

Cell Reports, 2019
Summary: Mammalian erythropoiesis yields a highly specialized cell type, the mature erythrocyte, evolved to meet the organismal needs of increased oxygen-carrying capacity.
Vincent P. Schulz, Hongxia Yan, Kimberly Lezon-Geyda, Xiuli An, John Hale, Christopher D. Hillyer, Narla Mohandas, Patrick G. Gallagher   +7 more
doaj   +1 more source

Examining the effect of red blood cell collisions using a fully eulerian simulation approach

, 2023
: Computational fluid dynamics simulations are employed using the volume of fluid multiphase approach to simulate the fluid structure interaction dynamics of red blood cells in a Couette shear flow.

core   +1 more source

Red blood cell extracellular vesicles as robust carriers of RNA-based therapeutics [PDF]

, 2018
One of the major challenges of RNA-based therapeutics is the method for delivery of RNA molecules. In a recent article (Nat Commun 9(1):2359), we described a novel delivery platform for RNA-based drugs using red blood cell extracellular vesicles which ...
Austin Lam, Minh TN Le, Xin Zhang, Chanh Tin Pham   +3 more
core   +1 more source

Whiteout: a social history of sickle cell disease in Ontario, Canada

Critical Public Health
What does it mean to develop health policies and services for diseases that are socially constructed as racialized in a country that continuously erases race?
Sinthu Srikanthan
doaj   +1 more source