Results 41 to 50 of about 262,252 (320)

AI-based approach for improving the detection of blood doping in sports [PDF]

arXiv, 2022
Sports officials around the world are facing incredible challenges due to the unfair means of practices performed by the athletes to improve their performance in the game. It includes the intake of hormonal based drugs or transfusion of blood to increase their strength and the result of their training.
arxiv  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Statistical methods for characterizing transfusion-related changes in regional oxygenation using Near-infrared spectroscopy (NIRS) in preterm infants [PDF]

, 2018
Near infrared spectroscopy (NIRS) is an imaging-based diagnostic tool that provides non-invasive and continuous evaluation of regional tissue oxygenation in real-time. In recent years, NIRS has show promise as a useful monitoring technology to help detect relative tissue ischemia that could lead to significant morbidity and mortality in preterm infants.
arxiv   +1 more source

Stress-strength reliability estimation for type-1 pathway generated exponential distribution with applications to AIDS incubation time [PDF]

arXiv, 2023
The Type-1 Pathway Generated Exponential distribution (PGE-1) is introduced. We have considered the estimate of the stress-strength parameter when the stress and strength components are statistically independent and follow PGE-1 distributions with distinct parameters.
arxiv  

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma

Cancer Medicine, Volume 11, Issue 24, Page 4889-4899, December 2022., 2022
This analysis assessed safety and efficacy of lisocabtagene maraleucel (liso‐cel), an autologous CD‐19‐directed CAR T‐cell product, in Japanese patients with R/R aggressive LBCL in Cohort 3 of TRANSCEND WORLD (NCT03484702). Liso‐cel demonstrated meaningful efficacy and a manageable safety profile in Japanese patients with R/R LBCL.
Shinichi Makita, Go Yamamoto, Dai Maruyama, Yuki Asano‐Mori, Daisuke Kaji, Revathi Ananthakrishnan, Ken Ogasawara, Lara Stepan, Claudia Schusterbauer, Nils Rettby, Jens Hasskarl, Koji Izutsu   +11 more
wiley   +1 more source

Demand Forecasting for Platelet Usage: from Univariate Time Series to Multivariate Models [PDF]

arXiv, 2021
Platelet products are both expensive and have very short shelf lives. As usage rates for platelets are highly variable, the effective management of platelet demand and supply is very important yet challenging. The primary goal of this paper is to present an efficient forecasting model for platelet demand at Canadian Blood Services (CBS).
arxiv  

On the Transfusion of Blood [PDF]

The Boston Medical and Surgical Journal
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openaire   +3 more sources

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

FEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla, Faiza Abbas, Luigia Rossi, Mauro Magnani, Sara Biagiotti   +4 more
wiley   +1 more source

Outcomes of simultaneous resection for elderly patients with colorectal liver metastasis: A propensity score matching analysis

Cancer Medicine, Volume 11, Issue 24, Page 4913-4926, December 2022., 2022
482 CRLM patients treated by simultaneous resection were categorized into the young group (age 70 years) and the elderly group (age GreaterEqual;70 years). Although elderly patients receiving simultaneous resection of CRLM have worse OS, similar PFS was reached in the multivariate analysis after propensity score matching.
Qichen Chen, Yizhou Zhang, Yiqiao Deng, Zhen Huang, Hong Zhao, Jianqiang Cai   +5 more
wiley   +1 more source

Haplotypes analysis reveals the genetic basis of type I CD36 deficiency

Scientific Reports
CD36, also known as glycoprotein IV, is classified into two distinct subgroups based on the presence or absence of its expression on monocytes. The CD36 gene spans approximately 50,000 base pairs.
Wenjie Xia, Dawei Chen, Xinnian Li, Jing Liu, Xiuzhang Xu, Xin Ye, Jing Deng, Haoqiang Ding, Hui Ren, Yangkai Chen, Huaqin Liang, Xingqiang Lai, Yongshui Fu   +12 more
doaj   +1 more source