Results 61 to 70 of about 2,676,121 (315)

Use of Topical (Intra-articular) Tranexamic Acid to Minimise Blood Loss and Transfusion in Total Knee Replacement Surgery [PDF]

open access: yes, 2010
Introduction Total knee replacement (TKR) is a common orthopaedic procedure, with 20-70% of patients needing 1-3 units of blood, although allogeneic transfusion is not risk free.
ALSHRYDA, SATTAR,JABER,MOHR   +1 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Application of closed-loop blood transfusion information system in the whole process management of blood transfusion

open access: yes, 2022
Objective To explore the effect of mobile transfusion closed-loop information system in the whole process management of clinical blood transfusion. Methods The hospital information system (HIS) of Soochow Hospital affiliated to Nanjing Medical University
Renchao HUO   +4 more
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Expert consensus on research of red blood cell transfusion refractoriness

open access: yesZhongguo shuxue zazhi
The incidence of red blood cell transfusion refractoriness (RTR) remains high in clinical practice. The occurrence of RTR not only impairs therapeutic efficacy and increases patients' financial burden, but also leads to the waste of blood resources ...
Expert consensus writing group on ineffective red blood cell transfusion
doaj   +1 more source

A guideline for transfusion of red blood cells in surgical patients

open access: yes, 2000
Blood transfusion carries a real but unquantifiable risk of adverse outcome in surgical patients from infectious, immunological and cardiorespiratory morbid events.
National Blood Users Group
core  

Blood transfusion service in Poland in 2019 [PDF]

open access: yes, 2020
Background: In this study we evaluated the basic aspects of the activity of the Polish Blood Transfusion Service (hereinafter referred to as Centers) in 2019. Materials and methods: Retrospective analysis of the 2019-data supplied by the Centers. Results:
Tomaszewska, Anna; Department of Transfusion Medicine, Institute of Hematology and Transfusion Medicine in Warsaw   +9 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Retrospective study on transfusion-related acute lung injury after intraoperative and postoperative blood transfusion in patients at a single medical center

open access: yesBMC Pulmonary Medicine
Introduction Transfusion-related acute lung injury (TRALI) is a life-threatening syndrome that occurs within six hours of a blood transfusion.
Jing Liu   +11 more
doaj   +1 more source

Blood Transfusion Service Board annual report 1998

open access: yes, 1998
The year under review was another difficult and challenging year for the Blood Transfusion Service Board. It was also the year in which many solid foundations were laid, which will assist in redeveloping and refocusing blood transfusion services in ...
Blood Transfusion Service Board
core  

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