Results 81 to 90 of about 4,631,334 (404)

Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2014
Since October 2013, French Polynesia has experienced the largest documented outbreak of Zika virus (ZIKAV) infection. To prevent transmission of ZIKAV by blood transfusion, specific nucleic acid testing of blood donors was implemented. From November 2013
D. Musso, T. Nhan, Emilie Robin, C. Roche, D. Bierlaire, Karen Zisou, A. S. Yan, Van-Mai Cao-Lormeau, J. Broult   +8 more
semanticscholar   +1 more source

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

Advanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun, Xiya Li, Shenjia Gao, Yi Jiang, Xinyi Wu, Zhaoyuan Chen, Han Wu, Qing Hua, Rui Zu, Huaijiang Xiang, Ronen Ben‐Ami, Changhong Miao, Li Tan, Ying Li, Jun Wang, Wankun Chen   +15 more
wiley   +1 more source

Restrictive versus liberal transfusion strategy for red blood cell transfusion: systematic review of randomised trials with meta-analysis and trial sequential analysis

British medical journal, 2015
Objective To compare the benefit and harm of restrictive versus liberal transfusion strategies to guide red blood cell transfusions. Design Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials.
L. Holst, Marie W Petersen, N. Haase, Anders Perner, Jørn Wetterslev   +4 more
semanticscholar   +2 more sources

A quantitative analysis of the factors that influence clinical blood demand in the Suzhou area

Scientific Reports
Maintaining an adequate blood supply is critical for health care systems, but clinical blood demand is influenced by dynamic, multilevel factors. The aim of this study was to identify and quantify the relationships among the factors that affect clinical ...
Shuhong Xie, Mingyuan Wang, Longhai Tang, Yiming Jin, Yan Cao, Wei Gao, Yu Yan, Qi Xiao, Weibin Yan   +8 more
doaj   +1 more source

Hemin regulates platelet clearance in hemolytic disease by binding to GPIbα

Platelets
Hemolysis is associated with thrombosis and vascular dysfunction, which are the pathological components of many diseases. Hemolytic products, including hemoglobin and hemin, activate platelets (PLT).
Man Zhao, Dongxin Peng, Yuxuan Li, Minwei He, Yulong Zhang, Qianqian Zhou, Sujing Sun, Ping Ma, Liping Lv, Xiaohui Wang, Linsheng Zhan   +10 more
doaj   +1 more source

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

Advanced Science, EarlyView.
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Chao Li, Emily G. Bache, Amy L. Apgar, Danielle M. Tufts, Tagbo H. R. Niepa   +4 more
wiley   +1 more source

Sorcin regulate pyroptosis by interacting with NLRP3 inflammasomes to facilitate the progression of hepatocellular carcinoma

Cell Death and Disease, 2023
A high recurrence rate and easy metastasis are two prominent clinical features of hepatocellular carcinoma (HCC), which is also the most common cause of cancer-related death. However, the molecular pathogenesis of HCC remains unclear.
Zhenfen Li, Ziyue Yang, Yuanyuan Zhu, Chunmeng Fu, Ning Li, Fang Peng   +5 more
doaj   +1 more source

Newly recognized causes of acute lung injury: transfusion of blood products, severe acute respiratory syndrome, and avian influenza. [PDF]

, 2006
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a clinical syndrome that has an ever-growing list of potential causes. The transfusion of blood products is often a life-saving therapy, but it can be associated with the development of ...
Looney, Mark R
core   +1 more source

Blood Transfusion Therapy

Medical Clinics of North America, 2017
Transfusion of red blood cells (RBCs) is a balance between providing benefit for patients while avoiding risks of transfusion. Randomized, controlled trials of restrictive RBC transfusion practices have shown equivalent patient outcomes compared with liberal transfusion practices, and meta-analyses have shown improved in-hospital mortality, reduced ...
Lawrence T. Goodnough, Anil K. Panigrahi
openaire   +3 more sources

Mechanically Active Hydrogel for Healing Intestinal Fistulas through the YAP‐Mediated Mechanosensitization of Intestinal Epithelial Cells

Advanced Science, EarlyView.
This study develops the hydrogel with antimicrobial, adhesive, degradable, injectable, and temperature‐sensitive contraction properties based on the transcriptomic and pathological characteristics of intestinal fistula patients. This hydrogel can seal rabbit intestinal fistula in situ, reduce the intestinal defect, and promote intestinal epithelial ...
Ze Li, Jiayang Li, Kang Chen, Guiwen Qu, Shuanghong Yang, Sicheng Li, Ye Liu, Yitian Teng, Rui Ma, Jinjian Huang, Peige Wang, Jianan Ren, Xiuwen Wu   +12 more
wiley   +1 more source