Results 91 to 100 of about 8,690,200 (215)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Heparin release kinetics in blood gas syringes [PDF]

, 2008
Background: In view of the urgency of results quality and operational availability of point of care analyzers is of high importance in ICUs and operational theatres. Methods: We investigated the influence of time on release and total amount of Heparin in
Bechmann, Volker, Gruber, Michael, Spaeth, Ruth   +2 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Human cord blood derived immature basophils show dual characteristics, expressing both basophil and eosinophil associated proteins [PDF]

, 2012
Basophils are blood cells of low abundance associated with allergy, inflammation and parasite infections. To study the transcriptome of mature circulating basophils cells were purified from buffy coats by density gradient centrifugations and two-step ...
Grundström Jeanette, Grundström, Jeanette, Reimer, JM, Sofia E Magnusson, Sofia E. Magnusson, Nilsson, Gunnar, Hellman, L, Wernersson, Sara, Wernersson, S, Magnusson, SE, Wernersson, Sara,, Nilsson Gunnar, Reimer Jenny M., Sara Wernersson, Grundström, Jeanette,, Jenny M. Reimer, Hellman, Lars,, Hellman, Lars, Wernersson Sara, Jenny M Reimer, Gunnar Nilsson, Nilsson, G,, Lars Hellman, Jeanette Grundström, Magnusson Sofia E., Magnusson, Sofia E., Grundstrom, J, Reimer, Jenny M., Reimer, Jenny M.,, Hellman Lars, Sveriges lantbruksuniversitet.   +30 more
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The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Ambulatory systolic blood pressure predicts left ventricular mass in type 2 diabetes, independently of central systolic blood pressure

, 2012
Objectives: Both ambulatory and central blood pressures have been reported to correlate more closely than office blood pressure with left ventricular mass index (LVMI).
Länne, Toste,, Östgren, Carl Johan,, Nyström, Fredrik,, Wijkman, Magnus,, Grodzinsky, Ewa,, Engvall, Jan,   +5 more
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Dietary Protein and Blood Pressure: A Systematic Review [PDF]

, 2010
Background - Elevated blood pressure (BP), which is a major risk factor for cardiovascular disease, is highly prevalent worldwide. Recently, interest has grown in the role of dietary protein in human BP.
Wieke Altorf-van der Kuil, Bakker, S.J.L., Bakker, Stephan J. L., Navis, G., Johanna M Geleijnse, Geleijnse, J.M., Baak, M.A. van, Geleijnse Johanna M., Kuil, W.A. van der, Bakker Stephan J. L., van't Veer, Pieter, Bakker, Stephan J. L.; id_orcid, Marleen A van Baak, Geleijnse, Johanna M., Mariëlle F Engberink, van Baak, M.A., Mariëlle F. Engberink, Engberink, Marielle F., Stephan J L Bakker, Altorf-van der Kuil, Wieke, van Baak Marleen A., Pieter van 't Veer, Brink, Elizabeth J., Wieke Altorf – van der Kuil, Bakker, S.J., van Baak, Marleen A., Johanna M. Geleijnse, Brink Elizabeth J., Veer, P., van 't, Engberink Mariëlle F., Brink, E.J., van 't Veer Pieter, Veer, P. van't, Gerjan Navis, van 't Veer, P., Marleen A. van Baak, Navis, Gerjan, Elizabeth J. Brink, Engberink, M.F., Stephan J. L. Bakker, van der Kuil, W., Navis Gerjan, Altorf-van der Kuil, W., Baak, M.A., van, Elizabeth J Brink, Altorf, W., Altorf – van der Kuil Wieke   +46 more
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Peningkatan Kewaspadaan Dini terhadap Anemia pada Lansia melalui Pemeriksaan Hemoglobin dan Golongan Darah

Jurnal Surya Masyarakat
Anemia is still a worldwide health issue. The high prevalence of anemia necessitates special attention because anemia can trigger a variety of health problems in the elderly.
Gela Setya Ayu Putri, Meutya Fajri Halmi, Chandra Eko Ardianto   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Blood Transfusion Service Board annual report 1998

, 1998
The year under review was another difficult and challenging year for the Blood Transfusion Service Board. It was also the year in which many solid foundations were laid, which will assist in redeveloping and refocusing blood transfusion services in ...
Blood Transfusion Service Board
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