The estimation of non‐protein nitrogen and urea nitrogen in blood
openaire +3 more sources
Establishment of a novel cynomolgus monkey model of hyperuricemia
We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang +12 more
wiley +1 more source
The association between blood urea nitrogen to albumin ratio and short- and long-term all-cause mortalities in acute pancreatitis: Insights from MIMIC-IV database. [PDF]
Zhang M +6 more
europepmc +1 more source
THE INCIDENCE, CAUSE, AND SIGNIFICANCE OF IMMEDIATE AND DELAYED OLIGURIA OR ANURIA AFTER HUMAN RENAL TRANSPLANTATION. [PDF]
HOLMES, JH +3 more
core
Challenges of modeling pristane‐induced lupus in non‐human primates
Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova +5 more
wiley +1 more source
Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde +11 more
wiley +2 more sources
Diagnostic value and prognostic significance of microRNA-210, serum creatinine, neutrophil gelatinase-associated lipocalin, blood urea nitrogen, cystatin C, and sequential organ failure assessment scores in patients with sepsis-associated acute kidney injury. [PDF]
Zhang Z, Zhang Z, Liu J, Qiao L, Fan X.
europepmc +1 more source
Objective Plasma biomarkers of Alzheimer's disease (AD) pathology are frequently tested in specialized research settings, which limits the generalizability of findings. Using electronic health records and banked plasma, we evaluated plasma biomarkers—phosphorylated tau 217 (p‐tau217), β‐amyloid 1–42/1–40 (Aβ42/Aβ40) and p‐tau217/Aβ42—in a real‐world ...
Katheryn A.Q. Cousins +12 more
wiley +1 more source
Relationship between blood urea nitrogen and 28-day all-cause mortality in patients with acute pulmonary edema: a retrospective analysis of the MIMIC-IV database. [PDF]
Tu G +5 more
europepmc +1 more source
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng +10 more
wiley +1 more source

