Results 71 to 80 of about 245,440 (308)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

DIETARY PROTEIN AND BLOOD UREA LEVELS IN RAT [PDF]

open access: yesIranian Journal of Public Health, 1973
Previous work by other investigators indicates a direct relation between the amount of protein in the diet and the level of urea in the blood . However, the present report shows that the type of protein , apart from its level in the ration , also has an ...
S. Vaghefi, Z. Nitson, O. Nickelsen
doaj   +2 more sources

The chronic kidney disease and acute kidney injury involvement in COVID-19 pandemic: A systematic review and meta-analysis.

open access: yesPLoS ONE, 2021
BackgroundCurrently, the SARS-CoV-2 promptly spread across China and around the world. However, there are controversies about whether preexisting chronic kidney disease (CKD) and acute kidney injury complication (AKI) are involved in the COVID-19 ...
Ya-Fei Liu   +6 more
doaj   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Study of calcium levels in patients with renal failure

open access: yesGomal Journal of Medical Sciences, 2012
Background: Renal failure and its consequences like renal osteodystrophy is a challenge for developing countries like Pakistan. The current study was aimed to evaluate the levels of serum calcium in patients with renal failure so that renal ...
Shahjahan   +5 more
doaj  

The effect of dietary nitrogen on nitrogen partitioning and milk production in grazing dairy cows : A thesis presented in partial fulfilment of the requirements for the Master of Animal Science at Massey University Palmerston North, New Zealand [PDF]

open access: yes, 2016
Two experiments were conducted during spring (8th October to 12th November 2009) as part of a larger study, to study the effects of increasing levels of crude protein (CP) in pasture on milk production, dry matter intake (DMI) and nitrogen (N ...
Hendriks, Stacey
core  

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Study on the relationship between milk urea nitrogen (MUN) and fertility in dairy cattle houses in Tabriz [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2011
The aim of this study was to assess the relationship between milk urea nitrogen (MUN) level and reproductive performance in high yielding dairy cattle houses in Tabriz, Iran. Among 213 selected dairy cattle, 76 heads (35.7%) have MUN < 16.00mg/dl (mean =
S Mosaferi, S Ettehad, H Kooshavar
doaj  

Blood Urea Nitrogen and Serum Creatinine [PDF]

open access: yesCirculation: Heart Failure, 2008
Klein and colleagues1 have retrospectively analyzed results derived from the prospective, randomized Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study and contribute an interesting article to this inaugural issue of Circulation: Heart Failure . Their analysis provides further evidence
openaire   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

open access: yesAdvanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil   +7 more
wiley   +1 more source

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