Results 161 to 170 of about 5,635,174 (391)

SIRT3 and RORα are two prospective targets against mitophagy during simulated ischemia/reperfusion injury in H9c2 cells

Heliyon
Autophagy during myocardial ischemia/reperfusion (MI/R) exacerbates cardiomyocyte injury. Melatonin (Mel) alleviates myocardial damage by regulating mitochondrial function and mitophagy, but the role of mitophagy in melatonin-induced cardioprotection ...
Jinjing Wu, Yanli Yang, Duomao Lin, Zhaoqi Wang, Jun Ma   +4 more
doaj   +1 more source

Buckling‐Resistant and Trace‐Stacked (BRATS) Design Enables Aid‐Free Implantation of Flexible Multielectrode Array with Minimized Inflammatory Tissue Response

Advanced Functional Materials, EarlyView.
Buckling‐resistant and trace‐stacked (BRATS) intracortical microelectrode arrays (MEAs) eliminate the need for insertion aid and complex surgical setup, resulting in minimal inflammatory tissue response, compared to conventional flexible MEAs inserted with aid. Trace stacking effectively doubled the channel count without increasing the MEA shank width,
May Yoon Pwint, Delin Shi, X. Tracy Cui
wiley   +1 more source

Tracking of the Internal Jugular Vein in Ultrasound Images Using Optical Flow

, 2017
Detection of relative changes in circulating blood volume is important to guide resuscitation and manage variety of medical conditions including sepsis, trauma, dialysis and congestive heart failure.
Karami, Ebrahim, Shehata, Mohamed, Smith, Andrew   +2 more
core   +1 more source

Rebuilding blood vessels [PDF]

Nature Biotechnology, 1999
openaire   +2 more sources

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Human blood vessel organoids as a model of diabetic vasculopathy

Nature, 2019
Reiner A. Wimmer, Alexandra Leopoldi, Martin Aichinger, N. Wick, B. Hantusch, M. Novatchkova, Jasmin Taubenschmid, M. Hämmerle, Christopher Esk, J. Bagley, Dominik Lindenhofer, Guibin Chen, M. Boehm, Chukwuma A. Agu, Fengtang Yang, B. Fu, J. Zuber, Juergen A. Knoblich, D. Kerjaschki, J. Penninger   +19 more
semanticscholar   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

The association of triglyceride–glucose index with major adverse cardiovascular and cerebrovascular events after acute myocardial infarction: a meta-analysis of cohort studies

Nutrition & Diabetes
Background Insulin resistance (IR) is indicated to be linked with adverse outcomes of acute myocardial infarction (AMI), for its pro-inflammatory and pro-thromboplastic function. The triglyceride-glucose (TyG) index is a newly developed substitute marker
Huiruo Liu, Liangshan Wang, Hong Wang, Xing Hao, Zhongtao Du, Chenglong Li, Xiaotong Hou   +6 more
doaj   +1 more source

Determination of the mechanical properties of the different layers of blood vessels in vivo.

, 1995
Y. C. Fung, S Q Liu
openalex   +2 more sources