Results 51 to 60 of about 5,445,600 (385)

A fractal graph model of capillary type systems

, 2017
We consider blood flow in a vessel with an attached capillary system. The latter is modeled with the help of a corresponding fractal graph whose edges are supplied with ordinary differential equations obtained by the dimension-reduction procedure from a ...
Kozlov, Vladimir, Nazarov, Sergei, Zavorokhin, German   +2 more
core   +1 more source

Particle-based simulation of ellipse-shaped particle aggregation as a model for vascular network formation [PDF]

, 2015
Computational modelling is helpful for elucidating the cellular mechanisms driving biological morphogenesis. Previous simulation studies of blood vessel growth based on the Cellular Potts model (CPM) proposed that elongated, adhesive or mutually ...
Merks, Roeland M. H., Palachanis, Dimitrios, Szabó, András   +2 more
core   +5 more sources

The Blood Vessels of the Skin

Journal of Investigative Dermatology, 1976
During the last 25 years, cutaneous biologists have been particularly interested in abnormal cutaneous vascular patterns, the profusion of capillary anastomoses, the leakiness of venules, clotting, fibrinolysis, and blood viscosity. As a result, the effects of hypoxia and the factors that encourage new vessel proliferation are better understood than ...
openaire   +3 more sources

Acetyl-L-carnitine ameliorates atherosclerosis in LDLR−/− mice by modulating cholesterol metabolism through SREBP2-dependent cholesterol biosynthesis

Frontiers in Nutrition
BackgroundAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of mortality globally. Hypercholesterolemia accelerates atherosclerotic development and is an independent modifiable risk factor for ASCVD.
Jingci Xing, Zhiyong Du, Fan Li, Fan Li, Yu Wang, Zihan Zhang, Xiaoqian Gao, Lijie Han, Xuechun Sun, Haili Sun, Yunhui Du, Chaowei Hu, Huahui Yu, Yanwen Qin   +13 more
doaj   +1 more source

ADRB2 polymorphisms and dyslipidemia risk in Chinese hypertensive patients

Clinical and Experimental Hypertension, 2017
Single nucleotide polymorphisms (SNPs) within a β-adrenergic receptor (ADRB2) were shown to be related to lipid traits or hyperlipidemia in different ethnicities, but not in a Chinese population. We performed the present study to investigate the possible
Wei Gu, Jilin Liu, Zuoguang Wang, Ya Liu, Shaojun Wen   +4 more
doaj   +1 more source

Successful revascularization versus medical therapy in diabetic patients with stable right coronary artery chronic total occlusion: a retrospective cohort study

Cardiovascular Diabetology, 2019
Background The territory of the right coronary artery (RCA) is smaller than that of the left anterior descending artery. Previous studies have reported conflicting results when considering whether stable RCA-chronic total occlusion (CTO) should be ...
Yunfeng Yan, Mingduo Zhang, Fei Yuan, Hong Liu, Di Wu, Yudong Fan, Xinjing Guo, Feng Xu, Min Zhang, Quanming Zhao, Shuzheng Lyu   +10 more
doaj   +1 more source

Development of retinal blood vessel segmentation methodology using wavelet transforms for assessment of diabetic retinopathy [PDF]

, 2005
Automated image processing has the potential to assist in the early detection of diabetes, by detecting changes in blood vessel diameter and patterns in the retina.
Bossomaier, T., Cesar, R.M., Jr., Cornforth, D.J., Cree, Michael J., Jelinek, Herbert J., Leandro, J.J.G., Mitchell, P., Soares, J.V.B.   +7 more
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Monocyte to high-density lipoprotein cholesterol ratio predicts poor outcomes in ischaemic heart failure patients combined with diabetes: a retrospective study

European Journal of Medical Research, 2023
Background The prevalence of ischaemic heart failure (HF) continues to increase. Diabetes mellitus (DM) concomitant with ischaemic HF increases the risk of major adverse cardiovascular events (MACEs). As a promising predictor for cardiovascular diseases,
Qiuyu Li, Xiaolong Lin, Xiaowen Bo, Fanqi Li, Siyuan Chen, Xuguang Miao, Donghui Zhao, Jinghua Liu, Qian Fan   +8 more
doaj   +1 more source