Results 91 to 100 of about 197,033 (294)

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

Online Prediction of Normal Blood Viscosity During Cardiopulmonary Bypass Using Hematocrit- and Temperature-Dependent Model

open access: yesIEEE Access, 2020
This paper proposes a mathematical model for online prediction of the hematocrit- and temperature-based normal blood viscosity during cardiopulmonary bypass (CPB).
Shigeyuki Okahara   +5 more
doaj   +1 more source

A new look at blood shear-thinning

open access: yes, 2016
Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear-thinning is intimately related to the dynamics and mutual interactions of red blood cells (RBCs), the major constituents of blood ...
Abkarian, Manouk   +8 more
core  

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli   +14 more
wiley   +1 more source

A Quasi-Mechanistic Mathematical Representation for Blood Viscosity

open access: yesFluids, 2017
Blood viscosity is a crucial element for any computation of flow fields in the vasculature or blood-wetted devices. Although blood is comprised of multiple elements, and its viscosity can vary widely depending on several factors, in practical ...
Samuel J. Hund   +2 more
doaj   +1 more source

Severity parameter and global importance factor of non-newtonian models in 3D reconstructed human left coronary artery [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011)   +4 more
core  

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Development of a Microfluidic Viscometer for Non-Newtonian Blood Analog Fluid Analysis

open access: yesBioengineering
The incidence of stroke is on the rise globally. This affects one in every four individuals each year, underscoring the urgent need for early warning and prevention systems.
Yii-Nuoh Chang, Da-Jeng Yao
doaj   +1 more source

Bridging the computational gap between mesoscopic and continuum modeling of red blood cells for fully resolved blood flow

open access: yes, 2019
We present a computational framework for the simulation of blood flow with fully resolved red blood cells (RBCs) using a modular approach that consists of a lattice Boltzmann solver for the blood plasma, a novel finite element based solver for the ...
Chopard, Bastien   +2 more
core   +2 more sources

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

open access: yesAdvanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter   +5 more
wiley   +1 more source

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