Results 71 to 80 of about 85,640 (259)

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Response of systemic hemodynamic parameters to changes in blood viscosity in spontaneously hypertensive rats

Бюллетень сибирской медицины
Aim. To study the response of systemic hemodynamic parameters to a decrease in blood viscosity in spontaneously hypertensive rats (SHR) compared to normotensive Wistar rats.Materials and methods.
A. V. Sidekhmenova, A. M. Anishchenko, O. I. Aliev, O. A. Ulyakhina, O. I. Poleshchuk, M. B. Plotnikov   +5 more
doaj   +1 more source

Rheological Properties of Blood in Patients with Diabetic Foot Ulcers Treated with Local Hyperbaric Oxygen Therapy - Preliminary Report [PDF]

Rehabilitacja Medyczna
Introduction: Physical medicine modalities constitute complementary therapy in treatment of diabetic foot ulcers. Any previous study assessed the influence of local hyperbaric oxygen therapy applied with Oxybaria-S device on blood rheology.
Grzegorz Onik, Katarzyna Knapik, Aleksander Sieroń, Karolina Sieroń   +3 more
doaj   +1 more source

Blood Viscosity in Waldenström’s Macroglobulinemia [PDF]

Blood, 1974
Abstract Erythrocytes and plasma proteins contribute to viscosity of blood. Therefore, blood viscosity was measured in 16 persons with macroglobulinemia with a cone-plate viscometer at defined shear rates. In each person a significant correlation (p < 0.001) was found between hematocrit and the logarithm of blood viscosity.
openaire   +2 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

In silico biophysics and rheology of blood and red blood cells in Gaucher Disease.

PLoS Computational Biology
Gaucher Disease (GD) is a rare genetic disorder characterized by a deficiency in the enzyme glucocerebrosidase, leading to the accumulation of glucosylceramide in various cells, including red blood cells (RBCs).
Zhaojie Chai, Guansheng Li, Papa Alioune Ndour, Philippe Connes, Pierre A Buffet, Melanie Franco, George Em Karniadakis   +6 more
doaj   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

Epidemiologic findings on blood viscosity.

Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 1984
In order to obtain basic knowledge about blood viscosity, which is changed by a variety of factors and disease, this study examined variations in blood viscosity. Sex, age, season, smoking, blood pressure, vibration syndrome, various diseases and exposure to cold were considered.Blood viscosity levels in several groups were measured with a cone-plate ...
openaire   +3 more sources